| Player | Team | Gm | IP | Ks | BBs | Hs | ERs | W | L | S | ERA | Ratio | DRAFT VALUE |
| Santana, Johan | MIN | 33 | 231.2 | 238 | 45 | 180 | 74 | 16 | 7 | 0 | 2.87 | 0.97 | $44 |
| Johnson, Randy | NYY | 34 | 225.2 | 211 | 47 | 207 | 95 | 17 | 8 | 0 | 3.79 | 1.13 | $37 |
| Clemens, Roger | HOU | 32 | 211.1 | 185 | 62 | 151 | 44 | 13 | 8 | 0 | 1.87 | 1.01 | $33 |
| Martinez, Pedro | NYM | 31 | 217 | 208 | 47 | 159 | 68 | 15 | 8 | 0 | 2.82 | 0.95 | $33 |
| Rivera, Mariano | NYY | 71 | 78.1 | 80 | 18 | 50 | 12 | 7 | 4 | 43 | 1.38 | 0.87 | $32 |
| Lidge, Brad | HOU | 70 | 70.2 | 103 | 23 | 58 | 18 | 4 | 4 | 42 | 2.29 | 1.15 | $31 |
| Carpenter, Chris | STL | 33 | 241.2 | 213 | 51 | 204 | 76 | 21 | 5 | 0 | 2.83 | 1.06 | $29 |
| Sheets, Ben | MLW | 22 | 156.2 | 141 | 25 | 142 | 58 | 10 | 9 | 0 | 3.33 | 1.07 | $28 |
| Nathan, Joe | MIN | 69 | 70 | 94 | 22 | 46 | 21 | 7 | 4 | 43 | 2.7 | 0.97 | $28 |
| Peavy, Jake | SD | 30 | 203 | 216 | 50 | 162 | 65 | 13 | 7 | 0 | 2.88 | 1.04 | $27 |
| Oswalt, Roy | HOU | 35 | 241.2 | 184 | 48 | 243 | 79 | 20 | 12 | 0 | 2.94 | 1.2 | $27 |
| Buehrle, Mark | CWS | 33 | 236.2 | 149 | 40 | 240 | 82 | 16 | 8 | 0 | 3.12 | 1.18 | $27 |
| Isringhausen, Jaso | STL | 63 | 59 | 51 | 27 | 43 | 14 | 1 | 2 | 39 | 2.14 | 1.19 | $26 |
| Smoltz, John | ATL | 33 | 229.2 | 169 | 53 | 210 | 78 | 14 | 7 | 0 | 3.06 | 1.15 | $26 |
| Zambrano, Carlos | CHC | 33 | 223.1 | 202 | 86 | 170 | 81 | 14 | 6 | 0 | 3.26 | 1.15 | $25 |
| Wagner, Billy | PHI | 75 | 77.2 | 87 | 20 | 45 | 13 | 4 | 3 | 38 | 1.51 | 0.84 | $25 |
| Hoffman, Trevor | SD | 60 | 57.2 | 54 | 12 | 52 | 19 | 1 | 6 | 43 | 2.97 | 1.11 | $25 |
| Cordero, Francisco | TEX | 69 | 69 | 79 | 30 | 61 | 26 | 3 | 1 | 37 | 3.39 | 1.32 | $23 |
| Schilling, Curt | BOS | 32 | 93.1 | 87 | 22 | 121 | 59 | 8 | 8 | 9 | 5.69 | 1.53 | $22 |
| Cordero, Chad | WAS | 74 | 74.1 | 61 | 17 | 55 | 15 | 2 | 4 | 47 | 1.82 | 0.97 | $22 |
| Garcia, Freddy | CWS | 33 | 228 | 146 | 60 | 225 | 98 | 14 | 8 | 0 | 3.87 | 1.25 | $22 |
| Colon, Bartolo | ANA | 33 | 222.2 | 157 | 43 | 215 | 86 | 21 | 8 | 0 | 3.48 | 1.16 | $22 |
| Benitez, Armando | SF | 30 | 30 | 23 | 16 | 25 | 15 | 2 | 3 | 19 | 4.5 | 1.37 | $21 |
| Radke, Brad | MIN | 31 | 200.2 | 117 | 23 | 214 | 90 | 9 | 12 | 0 | 4.04 | 1.18 | $21 |
| Gagne, Eric | LA | 14 | 13.1 | 22 | 3 | 10 | 4 | 1 | 0 | 8 | 2.7 | 0.98 | $20 |
| Rodriguez, Francis | ANA | 66 | 67.1 | 91 | 32 | 45 | 20 | 2 | 5 | 45 | 2.67 | 1.14 | $20 |
| Pettitte, Andy | HOU | 33 | 222.1 | 171 | 41 | 188 | 59 | 17 | 9 | 0 | 2.39 | 1.03 | $20 |
| Willis, Dontrelle | FLO | 34 | 236.1 | 170 | 55 | 213 | 69 | 22 | 10 | 0 | 2.63 | 1.13 | $20 |
| Schmidt, Jason | SF | 29 | 172 | 165 | 85 | 160 | 84 | 12 | 7 | 0 | 4.4 | 1.42 | $19 |
| Westbrook, Jake | CLE | 34 | 210.2 | 119 | 56 | 218 | 105 | 15 | 15 | 0 | 4.49 | 1.3 | $19 |
| Baez, Danys | TB | 67 | 72.1 | 51 | 30 | 66 | 23 | 5 | 4 | 41 | 2.86 | 1.33 | $18 |
| Zito, Barry | OAK | 35 | 228.1 | 171 | 89 | 185 | 98 | 14 | 13 | 0 | 3.86 | 1.2 | $17 |
| Garland, Jon | CWS | 32 | 221 | 115 | 47 | 212 | 86 | 18 | 10 | 0 | 3.5 | 1.17 | $17 |
| Harden, Rich | OAK | 22 | 128 | 121 | 43 | 93 | 36 | 10 | 5 | 0 | 2.53 | 1.06 | $17 |
| Sabathia, C.C. | CLE | 31 | 196.2 | 161 | 62 | 185 | 88 | 15 | 10 | 0 | 4.03 | 1.26 | $17 |
| Lackey, John | ANA | 33 | 209 | 199 | 71 | 208 | 80 | 14 | 5 | 0 | 3.44 | 1.33 | $16 |
| Beckett, Josh | FLO | 29 | 178.2 | 166 | 58 | 153 | 67 | 15 | 8 | 0 | 3.38 | 1.18 | $16 |
| Ryan, B.J. | BAL | 69 | 70.1 | 100 | 26 | 54 | 19 | 1 | 4 | 36 | 2.43 | 1.14 | $15 |
| Hudson, Tim | ATL | 29 | 192 | 115 | 65 | 194 | 75 | 14 | 9 | 0 | 3.52 | 1.35 | $15 |
| Foulke, Keith | BOS | 43 | 45.2 | 34 | 18 | 53 | 30 | 5 | 5 | 15 | 5.91 | 1.55 | $15 |
| Lieber, Jon | PHI | 35 | 218.1 | 149 | 41 | 223 | 102 | 17 | 13 | 0 | 4.2 | 1.21 | $15 |
| Jones, Todd | FLO | 68 | 73 | 62 | 14 | 61 | 17 | 1 | 5 | 40 | 2.1 | 1.03 | $15 |
| Mesa, Jose | PIT | 55 | 56.2 | 37 | 26 | 61 | 30 | 2 | 8 | 27 | 4.76 | 1.54 | $15 |
| Arroyo, Bronson | BOS | 35 | 205.1 | 100 | 54 | 213 | 103 | 14 | 10 | 0 | 4.51 | 1.3 | $15 |
| Maddux, Greg | CHC | 35 | 225 | 136 | 36 | 239 | 106 | 13 | 15 | 0 | 4.24 | 1.22 | $15 |
| Mulder, Mark | STL | 32 | 205 | 111 | 70 | 212 | 83 | 16 | 8 | 0 | 3.64 | 1.38 | $15 |
| Looper, Braden | NYM | 60 | 59.1 | 27 | 22 | 65 | 26 | 4 | 7 | 28 | 3.94 | 1.47 | $15 |
| Turnbow, Derrick | MLW | 69 | 67.1 | 64 | 24 | 49 | 13 | 7 | 1 | 39 | 1.74 | 1.08 | $15 |
| Wakefield, Tim | BOS | 33 | 225.1 | 151 | 68 | 210 | 104 | 16 | 12 | 0 | 4.15 | 1.23 | $15 |
| Halladay, Roy | TOR | 19 | 141.2 | 108 | 18 | 118 | 38 | 12 | 4 | 0 | 2.41 | 0.96 | $15 |
| Lopez, Rodrigo | BAL | 35 | 209.1 | 118 | 63 | 232 | 114 | 15 | 12 | 0 | 4.9 | 1.41 | $14 |
| Wells, David | BOS | 30 | 184 | 107 | 21 | 220 | 91 | 15 | 7 | 0 | 4.45 | 1.31 | $14 |
| Lee, Cliff | CLE | 32 | 202 | 143 | 52 | 194 | 85 | 18 | 5 | 0 | 3.79 | 1.22 | $14 |
| Gordon, Tom | NYY | 79 | 80.2 | 69 | 29 | 59 | 23 | 5 | 4 | 2 | 2.57 | 1.09 | $14 |
| Davis, Doug | MLW | 35 | 222.2 | 208 | 93 | 196 | 95 | 11 | 11 | 0 | 3.84 | 1.3 | $14 |
| Rogers, Ken | TEX | 30 | 195.1 | 87 | 53 | 205 | 75 | 14 | 8 | 0 | 3.46 | 1.32 | $14 |
| Silva, Carlos | MIN | 27 | 188.1 | 71 | 9 | 212 | 72 | 9 | 8 | 0 | 3.44 | 1.17 | $13 |
| Contreras, Jose | CWS | 32 | 204.2 | 154 | 75 | 177 | 82 | 15 | 7 | 0 | 3.61 | 1.23 | $13 |
| Weaver, Jeff | LA | 34 | 224 | 157 | 43 | 220 | 105 | 14 | 11 | 0 | 4.22 | 1.17 | $13 |
| Burnett, A.J. | FLO | 32 | 209 | 198 | 79 | 184 | 80 | 12 | 12 | 0 | 3.44 | 1.26 | $13 |
| Shields, Scot | ANA | 78 | 91.2 | 98 | 37 | 66 | 28 | 10 | 11 | 7 | 2.75 | 1.12 | $13 |
| Vazquez, Javier | ARZ | 33 | 215.2 | 192 | 46 | 223 | 106 | 11 | 15 | 0 | 4.42 | 1.25 | $13 |
| Guardado, Eddie | SEA | 58 | 56.1 | 48 | 15 | 52 | 17 | 2 | 3 | 36 | 2.72 | 1.19 | $13 |
| Linebrink, Scott | SD | 73 | 73.2 | 70 | 23 | 55 | 15 | 8 | 1 | 1 | 1.83 | 1.06 | $13 |
| Pavano, Carl | NYY | 17 | 100 | 56 | 18 | 129 | 53 | 4 | 6 | 0 | 4.77 | 1.47 | $13 |
| Bonderman, Jeremy | DET | 29 | 189 | 145 | 57 | 199 | 96 | 14 | 13 | 0 | 4.57 | 1.35 | $12 |
| Hermanson, Dustin | CWS | 57 | 57.1 | 33 | 17 | 46 | 13 | 2 | 4 | 34 | 2.04 | 1.1 | $12 |
| Escobar, Kelvim | ANA | 16 | 59.2 | 63 | 21 | 45 | 20 | 3 | 2 | 1 | 3.02 | 1.11 | $12 |
| Hernandez, Livan | WAS | 35 | 246.1 | 147 | 84 | 268 | 109 | 15 | 10 | 0 | 3.98 | 1.43 | $12 |
| Mussina, Mike | NYY | 30 | 179.2 | 142 | 47 | 199 | 88 | 13 | 8 | 0 | 4.41 | 1.37 | $12 |
| Rincon, Juan | MIN | 75 | 77 | 84 | 30 | 63 | 21 | 6 | 6 | 0 | 2.45 | 1.21 | $12 |
| Byrd, Paul | ANA | 31 | 204.1 | 102 | 28 | 216 | 85 | 12 | 11 | 0 | 3.74 | 1.19 | $12 |
| Clement, Matt | BOS | 32 | 191 | 146 | 68 | 192 | 97 | 13 | 6 | 0 | 4.57 | 1.36 | $12 |
| Hawkins, LaTroy | SF | 66 | 56.1 | 43 | 24 | 58 | 24 | 2 | 8 | 6 | 3.83 | 1.46 | $11 |
| Maroth, Mike | DET | 34 | 209 | 115 | 51 | 235 | 110 | 14 | 14 | 0 | 4.74 | 1.37 | $11 |
| Haren, Dan | OAK | 34 | 217 | 163 | 53 | 212 | 90 | 14 | 12 | 0 | 3.73 | 1.22 | $11 |
| Duchscherer, Justi | OAK | 65 | 85.2 | 85 | 19 | 67 | 21 | 7 | 4 | 5 | 2.21 | 1 | $11 |
| Glavine, Tom | NYM | 33 | 211.1 | 105 | 61 | 227 | 83 | 13 | 13 | 0 | 3.53 | 1.36 | $11 |
| Washburn, Jarrod | ANA | 29 | 177.1 | 94 | 51 | 184 | 63 | 8 | 8 | 0 | 3.2 | 1.33 | $11 |
| Suppan, Jeff | STL | 32 | 194.1 | 114 | 63 | 206 | 77 | 16 | 10 | 0 | 3.57 | 1.38 | $10 |
| Millwood, Kevin | CLE | 30 | 192 | 146 | 52 | 182 | 61 | 9 | 11 | 0 | 2.86 | 1.22 | $10 |
| Prior, Mark | CHC | 27 | 166.2 | 188 | 59 | 143 | 68 | 11 | 7 | 0 | 3.67 | 1.21 | $10 |
| Dempster, Ryan | CHC | 63 | 92 | 89 | 49 | 83 | 32 | 5 | 3 | 33 | 3.13 | 1.43 | $10 |
| Fuentes, Brian | COL | 78 | 74.1 | 91 | 34 | 59 | 24 | 2 | 5 | 31 | 2.91 | 1.25 | $10 |
| Webb, Brandon | ARZ | 33 | 229 | 172 | 59 | 229 | 90 | 14 | 12 | 0 | 3.54 | 1.26 | $10 |
| Perez, Odalis | LA | 19 | 108.2 | 74 | 28 | 109 | 55 | 7 | 8 | 0 | 4.56 | 1.26 | $10 |
| Penny, Brad | LA | 29 | 175.1 | 122 | 41 | 185 | 76 | 7 | 9 | 0 | 3.9 | 1.29 | $10 |
| Patterson, John | WAS | 31 | 198.1 | 185 | 65 | 172 | 69 | 9 | 7 | 0 | 3.13 | 1.19 | $10 |
| Myers, Brett | PHI | 34 | 215.1 | 208 | 68 | 193 | 89 | 13 | 8 | 0 | 3.72 | 1.21 | $10 |
| Batista, Miguel | TOR | 71 | 74.2 | 54 | 27 | 80 | 34 | 5 | 8 | 31 | 4.1 | 1.43 | $10 |
| Lilly, Ted | TOR | 25 | 126.1 | 96 | 58 | 135 | 78 | 10 | 11 | 0 | 5.56 | 1.53 | $10 |
| Street, Huston | OAK | 67 | 78.1 | 72 | 26 | 53 | 15 | 5 | 1 | 23 | 1.72 | 1.01 | $9 |
| Robertson, Nate | DET | 32 | 196.2 | 122 | 65 | 202 | 98 | 7 | 16 | 0 | 4.48 | 1.36 | $9 |
| Wickman, Bob | CLE | 64 | 62 | 41 | 21 | 57 | 17 | 0 | 4 | 45 | 2.47 | 1.26 | $9 |
| Blanton, Joe | OAK | 33 | 201.1 | 116 | 67 | 178 | 79 | 12 | 12 | 0 | 3.53 | 1.22 | $9 |
| Morris, Matt | STL | 31 | 192.2 | 117 | 37 | 209 | 88 | 14 | 10 | 0 | 4.11 | 1.28 | $9 |
| Perez, Oliver | PIT | 20 | 103 | 97 | 70 | 102 | 67 | 7 | 5 | 0 | 5.85 | 1.67 | $9 |
| Torres, Salomon | PIT | 78 | 94.2 | 55 | 36 | 76 | 29 | 5 | 5 | 3 | 2.76 | 1.18 | $9 |
| Towers, Josh | TOR | 33 | 208.2 | 112 | 29 | 237 | 86 | 13 | 12 | 0 | 3.71 | 1.27 | $9 |
| Chen, Bruce | BAL | 34 | 197.1 | 133 | 63 | 187 | 84 | 13 | 10 | 0 | 3.83 | 1.27 | $9 |
| Marquis, Jason | STL | 33 | 207 | 100 | 69 | 206 | 95 | 13 | 14 | 0 | 4.13 | 1.33 | $9 |
| Ayala, Luis | WAS | 68 | 71 | 40 | 14 | 75 | 21 | 8 | 7 | 1 | 2.66 | 1.25 | $8 |
| Lowry, Noah | SF | 33 | 204.2 | 172 | 76 | 193 | 86 | 13 | 13 | 0 | 3.78 | 1.31 | $8 |
| Lowe, Derek | LA | 35 | 222 | 146 | 55 | 223 | 89 | 12 | 15 | 0 | 3.61 | 1.25 | $8 |
| Moyer, Jamie | SEA | 32 | 200 | 102 | 52 | 225 | 95 | 13 | 7 | 0 | 4.28 | 1.39 | $8 |
| Madson, Ryan | PHI | 78 | 87 | 79 | 25 | 84 | 40 | 6 | 5 | 0 | 4.14 | 1.25 | $8 |
| Valverde, Jose | ARZ | 61 | 66.1 | 75 | 20 | 51 | 18 | 3 | 4 | 15 | 2.44 | 1.07 | $8 |
| Takatsu, Shingo | CWS | 31 | 28.2 | 32 | 16 | 30 | 19 | 1 | 2 | 8 | 5.97 | 1.6 | $8 |
| Timlin, Mike | BOS | 81 | 80.1 | 59 | 20 | 86 | 20 | 7 | 3 | 13 | 2.24 | 1.32 | $7 |
| Benson, Kris | NYM | 28 | 174.1 | 95 | 49 | 171 | 80 | 10 | 8 | 0 | 4.13 | 1.26 | $7 |
| Percival, Troy | DET | 26 | 25 | 20 | 11 | 19 | 16 | 1 | 3 | 8 | 5.76 | 1.2 | $7 |
| Takatsu, Shingo | NYM | 9 | 7.2 | 6 | 3 | 11 | 2 | 1 | 0 | 0 | 2.35 | 1.83 | $7 |
| Otsuka, Akinori | SD | 66 | 62.2 | 60 | 34 | 55 | 25 | 2 | 8 | 1 | 3.59 | 1.42 | $7 |
| Chacin, Adolfo | TOR | 34 | 203 | 121 | 70 | 213 | 84 | 13 | 9 | 0 | 3.72 | 1.39 | $7 |
| Young, Chris | TEX | 31 | 164.2 | 137 | 45 | 162 | 78 | 12 | 7 | 0 | 4.26 | 1.26 | $7 |
| Urbina, Ugueth | PHI | 56 | 52.1 | 66 | 25 | 35 | 24 | 4 | 3 | 1 | 4.13 | 1.15 | $7 |
| Loaiza, Esteban | WAS | 34 | 217 | 173 | 55 | 227 | 91 | 12 | 10 | 0 | 3.77 | 1.3 | $7 |
| Harang, Aaron | CIN | 32 | 211.2 | 163 | 51 | 217 | 90 | 11 | 13 | 0 | 3.83 | 1.27 | $7 |
| Capuano, Chris | MLW | 35 | 219 | 176 | 91 | 212 | 97 | 18 | 12 | 0 | 3.99 | 1.38 | $7 |
| Sosa, Jorge | ATL | 44 | 134 | 85 | 64 | 122 | 38 | 13 | 3 | 0 | 2.55 | 1.39 | $7 |
| Carrasco, Hector | WAS | 64 | 88.1 | 75 | 38 | 59 | 20 | 5 | 4 | 2 | 2.04 | 1.1 | $6 |
| Graves, Danny | NYM | 40 | 38.2 | 20 | 20 | 59 | 28 | 1 | 1 | 10 | 6.52 | 2.04 | $6 |
| Heilman, Aaron | NYM | 53 | 108 | 106 | 37 | 87 | 38 | 5 | 3 | 5 | 3.17 | 1.15 | $6 |
| Wright, Jaret | NYY | 13 | 63.2 | 34 | 32 | 81 | 43 | 5 | 5 | 0 | 6.08 | 1.77 | $6 |
| Johnson, Jason | DET | 33 | 210 | 93 | 49 | 233 | 106 | 8 | 13 | 0 | 4.54 | 1.34 | $6 |
| MacDougal, Mike | KC | 68 | 70.1 | 72 | 24 | 69 | 26 | 5 | 6 | 21 | 3.33 | 1.32 | $6 |
| Duke, Zach | PIT | 14 | 84.2 | 58 | 23 | 79 | 17 | 8 | 2 | 0 | 1.81 | 1.2 | $6 |
| Seo, Jae | NYM | 14 | 90.1 | 59 | 16 | 84 | 26 | 8 | 2 | 0 | 2.59 | 1.11 | $6 |
| Riske, David | CLE | 58 | 72.2 | 48 | 15 | 55 | 25 | 3 | 4 | 1 | 3.1 | 0.96 | $6 |
| Howry, Bob | CLE | 79 | 73 | 48 | 16 | 49 | 20 | 7 | 4 | 3 | 2.47 | 0.89 | $6 |
| Weathers, David | CIN | 73 | 77.2 | 61 | 29 | 71 | 34 | 7 | 4 | 15 | 3.94 | 1.29 | $6 |
| Tavarez, Julian | STL | 74 | 65.2 | 47 | 19 | 68 | 25 | 2 | 3 | 4 | 3.43 | 1.32 | $6 |
| Wood, Kerry | CHC | 21 | 66 | 77 | 26 | 52 | 31 | 3 | 4 | 0 | 4.23 | 1.18 | $6 |
| Kazmir, Scott | TB | 32 | 186 | 174 | 100 | 172 | 78 | 10 | 9 | 0 | 3.77 | 1.46 | $6 |
| Reyes, Al | STL | 65 | 62.2 | 67 | 20 | 38 | 15 | 4 | 2 | 3 | 2.15 | 0.93 | $6 |
| Urbina, Ugueth | DET | 25 | 27.1 | 31 | 14 | 21 | 8 | 1 | 3 | 9 | 2.63 | 1.28 | $6 |
| Walker, Tyler | SF | 67 | 61.2 | 54 | 27 | 68 | 29 | 6 | 4 | 23 | 4.23 | 1.54 | $6 |
| Bush, David | TOR | 25 | 136.1 | 75 | 29 | 142 | 68 | 5 | 11 | 0 | 4.49 | 1.25 | $6 |
| Hernandez, Roberto | NYM | 67 | 69.2 | 61 | 28 | 57 | 20 | 8 | 6 | 4 | 2.58 | 1.22 | $5 |
| Hernandez, Orlando | CWS | 24 | 128.1 | 91 | 50 | 137 | 73 | 9 | 9 | 1 | 5.12 | 1.46 | $5 |
| Mota, Guillermo | FLO | 56 | 67 | 60 | 32 | 65 | 35 | 2 | 2 | 2 | 4.7 | 1.45 | $5 |
| Worrell, Tim | ARZ | 51 | 48.2 | 39 | 12 | 59 | 22 | 1 | 2 | 1 | 4.07 | 1.46 | $5 |
| Wheeler, Dan | HOU | 71 | 73.1 | 69 | 19 | 53 | 18 | 2 | 3 | 3 | 2.21 | 0.98 | $5 |
| Frasor, Jason | TOR | 67 | 74.2 | 62 | 28 | 67 | 27 | 3 | 5 | 1 | 3.25 | 1.27 | $5 |
| Thomson, John | ATL | 17 | 98.2 | 61 | 28 | 111 | 49 | 4 | 6 | 0 | 4.47 | 1.41 | $5 |
| Eaton, Adam | SD | 24 | 128.2 | 100 | 44 | 140 | 61 | 11 | 5 | 0 | 4.27 | 1.43 | $5 |
| Elarton, Scott | CLE | 31 | 181.2 | 103 | 48 | 189 | 93 | 11 | 9 | 0 | 4.61 | 1.3 | $5 |
| Crain, Jesse | MIN | 75 | 79.2 | 25 | 29 | 61 | 24 | 12 | 5 | 1 | 2.71 | 1.13 | $5 |
| Cabrera, Daniel | BAL | 29 | 161.1 | 157 | 87 | 144 | 81 | 10 | 13 | 0 | 4.52 | 1.43 | $5 |
| Brazoban, Yhency | LA | 74 | 72.2 | 61 | 32 | 70 | 43 | 4 | 10 | 21 | 5.33 | 1.4 | $5 |
| Speier, Justin | TOR | 65 | 66.2 | 56 | 15 | 48 | 19 | 3 | 2 | 0 | 2.57 | 0.95 | $5 |
| Gonzalez, Mike | PIT | 51 | 50 | 58 | 31 | 35 | 15 | 1 | 3 | 3 | 2.7 | 1.32 | $5 |
| Fultz, Aaron | PHI | 62 | 72.1 | 54 | 23 | 47 | 18 | 4 | 0 | 0 | 2.24 | 0.97 | $5 |
| Betancourt, Rafael | CLE | 54 | 67.2 | 73 | 17 | 57 | 21 | 4 | 3 | 1 | 2.79 | 1.09 | $5 |
| Politte, Cliff | CWS | 68 | 67.1 | 57 | 21 | 42 | 15 | 7 | 1 | 1 | 2 | 0.94 | $5 |
| Drese, Ryan | WAS | 11 | 59.2 | 26 | 22 | 66 | 33 | 3 | 6 | 0 | 4.98 | 1.47 | $5 |
| Reitsma, Chris | ATL | 76 | 73.1 | 42 | 14 | 79 | 32 | 3 | 6 | 15 | 3.93 | 1.27 | $5 |
| Greinke, Zack | KC | 33 | 183 | 114 | 53 | 233 | 118 | 5 | 17 | 0 | 5.8 | 1.56 | $5 |
| Calero, Kiko | OAK | 58 | 55.2 | 52 | 18 | 45 | 20 | 4 | 1 | 1 | 3.23 | 1.13 | $5 |
| Seanez, Rudy | SD | 57 | 60.1 | 84 | 22 | 49 | 18 | 7 | 1 | 0 | 2.69 | 1.18 | $5 |
| Hernandez, Felix | SEA | 12 | 84.1 | 77 | 23 | 61 | 25 | 4 | 4 | 0 | 2.67 | 1 | $5 |
| Carrara, Giovanni | LA | 72 | 75.2 | 56 | 38 | 65 | 33 | 7 | 4 | 0 | 3.93 | 1.36 | $4 |
| Wise, Matt | MLW | 49 | 64.1 | 62 | 25 | 37 | 24 | 4 | 4 | 1 | 3.36 | 0.96 | $4 |
| Tomko, Brett | SF | 33 | 190.2 | 114 | 57 | 205 | 95 | 8 | 15 | 1 | 4.48 | 1.37 | $4 |
| Santana, Ervin | ANA | 23 | 133.2 | 99 | 47 | 139 | 69 | 12 | 8 | 0 | 4.65 | 1.39 | $4 |
| Donnelly, Brendan | ANA | 65 | 65.1 | 53 | 19 | 60 | 27 | 9 | 3 | 0 | 3.72 | 1.21 | $4 |
| Chacon, Shawn | NYY | 14 | 79 | 40 | 30 | 66 | 25 | 7 | 3 | 0 | 2.85 | 1.22 | $4 |
| Marte, Damaso | CWS | 66 | 45.1 | 54 | 33 | 45 | 19 | 3 | 4 | 4 | 3.77 | 1.72 | $4 |
| Lohse, Kyle | MIN | 31 | 178.2 | 86 | 44 | 211 | 83 | 9 | 13 | 0 | 4.18 | 1.43 | $4 |
| Bedard, Erik | BAL | 24 | 141.2 | 125 | 57 | 139 | 63 | 6 | 8 | 0 | 4 | 1.38 | $4 |
| Farnsworth, Kyle | ATL | 26 | 27.1 | 32 | 7 | 15 | 6 | 0 | 0 | 10 | 1.98 | 0.8 | $4 |
| Loe, Kameron | TEX | 48 | 92 | 45 | 31 | 89 | 35 | 9 | 6 | 1 | 3.42 | 1.3 | $4 |
| Wang, Chien-Ming | NYY | 18 | 116.1 | 47 | 32 | 113 | 52 | 8 | 5 | 0 | 4.02 | 1.25 | $4 |
| Small, Aaron | NYY | 15 | 76 | 37 | 24 | 71 | 27 | 10 | 0 | 0 | 3.2 | 1.25 | $4 |
| Saarloos, Kirk | OAK | 29 | 159.2 | 53 | 54 | 170 | 74 | 10 | 9 | 0 | 4.17 | 1.4 | $4 |
| Lidle, Cory | PHI | 31 | 184.2 | 121 | 40 | 210 | 93 | 13 | 11 | 0 | 4.53 | 1.35 | $4 |
| Drese, Ryan | TEX | 12 | 69.2 | 20 | 24 | 96 | 50 | 4 | 6 | 0 | 6.46 | 1.72 | $3 |
| Qualls, Chad | HOU | 77 | 79.2 | 60 | 23 | 73 | 29 | 6 | 4 | 0 | 3.28 | 1.21 | $3 |
| Ohka, Tomokazu | MLW | 32 | 180.1 | 98 | 55 | 189 | 81 | 11 | 9 | 0 | 4.04 | 1.35 | $3 |
| Williams, Woody | SD | 28 | 159.2 | 106 | 51 | 174 | 86 | 9 | 12 | 0 | 4.85 | 1.41 | $3 |
| Eyre, Scott | SF | 86 | 68.1 | 65 | 26 | 48 | 20 | 2 | 2 | 0 | 2.63 | 1.08 | $3 |
| Sanchez, Duaner | LA | 79 | 82 | 71 | 36 | 75 | 34 | 4 | 7 | 8 | 3.73 | 1.35 | $3 |
| Mateo, Julio | SEA | 55 | 88.1 | 52 | 17 | 79 | 30 | 3 | 6 | 0 | 3.06 | 1.09 | $3 |
| Williams, Jerome | CHC | 22 | 122.2 | 70 | 49 | 119 | 58 | 6 | 10 | 0 | 4.26 | 1.37 | $3 |
| Julio, Jorge | BAL | 67 | 71.2 | 58 | 24 | 76 | 47 | 3 | 5 | 0 | 5.9 | 1.4 | $3 |
| Rusch, Glendon | CHC | 46 | 145.1 | 111 | 53 | 175 | 73 | 9 | 8 | 0 | 4.52 | 1.57 | $3 |
| Leiter, Al | NYY | 16 | 62.1 | 45 | 38 | 66 | 38 | 4 | 5 | 0 | 5.49 | 1.67 | $3 |
| Hendrickson, Mark | TB | 31 | 178.1 | 89 | 49 | 227 | 117 | 11 | 8 | 0 | 5.9 | 1.55 | $3 |
| Lawrence, Brian | SD | 33 | 195.2 | 109 | 57 | 211 | 105 | 7 | 15 | 0 | 4.83 | 1.37 | $3 |
| Cotts, Neal | CWS | 69 | 60.1 | 58 | 29 | 38 | 13 | 4 | 0 | 0 | 1.94 | 1.11 | $3 |
| Pineiro, Joel | SEA | 30 | 189 | 107 | 56 | 224 | 118 | 7 | 11 | 0 | 5.62 | 1.48 | $3 |
| Fossum, Casey | TB | 36 | 162.2 | 128 | 60 | 170 | 89 | 8 | 12 | 0 | 4.92 | 1.41 | $3 |
| Hammond, Chris | SD | 55 | 58.2 | 34 | 14 | 51 | 25 | 5 | 1 | 0 | 3.84 | 1.11 | $3 |
| Villone, Ron | SEA | 52 | 40.1 | 41 | 23 | 33 | 11 | 2 | 3 | 1 | 2.45 | 1.39 | $3 |
| King, Ray | STL | 77 | 40 | 23 | 16 | 46 | 15 | 4 | 4 | 0 | 3.38 | 1.55 | $3 |
| Thompson, Brad | STL | 40 | 55 | 29 | 15 | 46 | 18 | 4 | 0 | 1 | 2.95 | 1.11 | $3 |
| Cain, Matt | SF | 7 | 46.1 | 30 | 19 | 24 | 12 | 2 | 1 | 0 | 2.33 | 0.93 | $3 |
| Franklin, Ryan | SEA | 32 | 190.2 | 93 | 62 | 212 | 108 | 8 | 15 | 0 | 5.1 | 1.44 | $3 |
| Mercker, Kent | CIN | 78 | 61.2 | 45 | 19 | 64 | 25 | 3 | 1 | 4 | 3.65 | 1.35 | $3 |
| Padilla, Juan | NYM | 24 | 36.1 | 17 | 13 | 24 | 6 | 3 | 1 | 1 | 1.49 | 1.02 | $3 |
| Wuertz, Michael | CHC | 75 | 75.2 | 89 | 40 | 60 | 32 | 6 | 2 | 0 | 3.81 | 1.32 | $3 |
| Benoit, Joaquin | TEX | 32 | 87 | 78 | 38 | 69 | 36 | 4 | 4 | 0 | 3.72 | 1.23 | $2 |
| Brown, Kevin | NYY | 13 | 73.1 | 50 | 19 | 107 | 53 | 4 | 7 | 0 | 6.5 | 1.72 | $2 |
| Vizcaino, Luis | CWS | 65 | 70 | 43 | 29 | 74 | 29 | 6 | 5 | 0 | 3.73 | 1.47 | $2 |
| Medders, Brandon | ARZ | 27 | 30.1 | 31 | 11 | 21 | 6 | 4 | 1 | 0 | 1.78 | 1.05 | $2 |
| Romero, J.C. | MIN | 68 | 57 | 48 | 39 | 50 | 22 | 4 | 3 | 0 | 3.47 | 1.56 | $2 |
| Dotel, Octavio | OAK | 15 | 15.1 | 16 | 11 | 10 | 6 | 1 | 2 | 7 | 3.52 | 1.37 | $2 |
| Claussen, Brandon | CIN | 29 | 166.2 | 121 | 57 | 178 | 78 | 10 | 11 | 0 | 4.21 | 1.41 | $2 |
| Helling, Rick | MLW | 15 | 49 | 42 | 18 | 39 | 13 | 3 | 1 | 0 | 2.39 | 1.16 | $2 |
| Walker, Pete | TOR | 41 | 84 | 43 | 33 | 81 | 33 | 6 | 6 | 2 | 3.54 | 1.36 | $2 |
| Hensley, Clay | SD | 24 | 47.2 | 28 | 17 | 33 | 9 | 1 | 1 | 0 | 1.7 | 1.05 | $2 |
| Kennedy, Joe | OAK | 19 | 60.2 | 45 | 20 | 64 | 30 | 4 | 5 | 0 | 4.45 | 1.38 | $2 |
| Majewski, Gary | WAS | 79 | 86 | 50 | 37 | 80 | 28 | 4 | 4 | 1 | 2.93 | 1.36 | $2 |
| Williams, Todd | BAL | 72 | 76.1 | 38 | 26 | 72 | 28 | 5 | 5 | 1 | 3.3 | 1.28 | $2 |
| Rodney, Fernando | DET | 39 | 44 | 42 | 17 | 39 | 14 | 2 | 3 | 9 | 2.86 | 1.27 | $2 |
| Alvarez, Wilson | LA | 21 | 24 | 16 | 7 | 31 | 15 | 1 | 4 | 0 | 5.63 | 1.58 | $2 |
| Farnsworth, Jeff | DET | 46 | 42.2 | 55 | 20 | 29 | 11 | 1 | 1 | 6 | 2.32 | 1.15 | $2 |
| Maholm, Paul | PIT | 6 | 41.1 | 26 | 17 | 31 | 10 | 3 | 1 | 0 | 2.18 | 1.16 | $2 |
| Williams, Dave | PIT | 25 | 138.2 | 88 | 58 | 137 | 68 | 10 | 11 | 0 | 4.41 | 1.41 | $2 |
| Meche, Gil | SEA | 29 | 143.1 | 83 | 72 | 153 | 81 | 10 | 8 | 0 | 5.09 | 1.57 | $2 |
| Kline, Steve | BAL | 67 | 61 | 36 | 30 | 59 | 29 | 2 | 4 | 0 | 4.28 | 1.46 | $2 |
| Rhodes, Arthur | CLE | 47 | 43.1 | 43 | 12 | 33 | 10 | 3 | 1 | 0 | 2.08 | 1.04 | $2 |
| Putz, J.J. | SEA | 64 | 60 | 45 | 23 | 58 | 24 | 6 | 5 | 1 | 3.6 | 1.35 | $2 |
| Spurling, Chris | DET | 56 | 70.2 | 26 | 22 | 58 | 27 | 3 | 4 | 0 | 3.44 | 1.13 | $2 |
| Flores, Randy | STL | 50 | 41.2 | 43 | 13 | 37 | 16 | 3 | 1 | 1 | 3.46 | 1.2 | $2 |
| Redman, Mark | PIT | 30 | 178.1 | 101 | 56 | 188 | 97 | 5 | 15 | 0 | 4.9 | 1.37 | $1 |
| Wasdin, John | TEX | 31 | 75.2 | 44 | 20 | 77 | 36 | 3 | 2 | 4 | 4.28 | 1.28 | $1 |
| Tejeda, Robinson | PHI | 26 | 85.2 | 72 | 51 | 67 | 34 | 4 | 3 | 0 | 3.57 | 1.38 | $1 |
| Trachsel, Steve | NYM | 6 | 37 | 24 | 12 | 37 | 17 | 1 | 4 | 0 | 4.14 | 1.32 | $1 |
| Miller, Matt J. | CLE | 23 | 29.2 | 23 | 10 | 22 | 6 | 1 | 0 | 1 | 1.82 | 1.08 | $1 |
| Downs, Scott | TOR | 26 | 94 | 75 | 34 | 93 | 45 | 4 | 3 | 0 | 4.31 | 1.35 | $1 |
| Villone, Ron | FLO | 27 | 23.2 | 29 | 12 | 24 | 18 | 3 | 2 | 0 | 6.85 | 1.52 | $1 |
| Walker, Jamie | DET | 66 | 48.2 | 30 | 13 | 49 | 20 | 4 | 3 | 0 | 3.7 | 1.27 | $1 |
| Hampton, Mike | ATL | 12 | 69.1 | 27 | 18 | 74 | 27 | 5 | 3 | 0 | 3.5 | 1.33 | $1 |
| Astacio, Pedro | SD | 12 | 59.2 | 33 | 26 | 54 | 21 | 4 | 2 | 0 | 3.17 | 1.34 | $1 |
| Cook, Aaron | COL | 13 | 83.1 | 24 | 16 | 101 | 34 | 7 | 2 | 0 | 3.67 | 1.4 | $1 |
| Jenks, Bobby | CWS | 32 | 39.1 | 50 | 15 | 34 | 12 | 1 | 1 | 6 | 2.75 | 1.25 | $1 |
| Boyer, Blaine | ATL | 43 | 37.2 | 33 | 17 | 32 | 13 | 4 | 2 | 0 | 3.11 | 1.3 | $1 |
| Cortes, David | COL | 50 | 52.2 | 36 | 10 | 50 | 24 | 2 | 0 | 2 | 4.1 | 1.14 | $1 |
| Miller, Wade | BOS | 16 | 91 | 64 | 47 | 96 | 50 | 4 | 4 | 0 | 4.95 | 1.57 | $1 |
| McCarthy, Brandon | CWS | 12 | 67 | 48 | 17 | 62 | 30 | 3 | 2 | 0 | 4.03 | 1.18 | $1 |
| Springer, Russ | HOU | 62 | 59 | 54 | 21 | 49 | 31 | 4 | 4 | 0 | 4.73 | 1.19 | $1 |
| Ohman, Will | CHC | 69 | 43.1 | 45 | 24 | 32 | 14 | 2 | 2 | 0 | 2.91 | 1.29 | $1 |
| Rauch, Jon | WAS | 15 | 30 | 23 | 11 | 24 | 12 | 2 | 4 | 0 | 3.6 | 1.17 | $1 |
| Accardo, Jeremy | SF | 28 | 29.2 | 16 | 9 | 26 | 13 | 1 | 5 | 0 | 3.94 | 1.18 | $1 |
| Acevedo, Jose | COL | 36 | 64 | 31 | 16 | 86 | 46 | 2 | 4 | 1 | 6.47 | 1.59 | $1 |
| Adams, Mike | MLW | 13 | 13.1 | 14 | 10 | 12 | 4 | 0 | 1 | 1 | 2.7 | 1.65 | $1 |
| Adams, Terry | PHI | 16 | 13.1 | 4 | 10 | 25 | 19 | 0 | 2 | 0 | 12.83 | 2.63 | $1 |
| Adkins, Jon | CWS | 5 | 8.1 | 1 | 4 | 13 | 8 | 0 | 1 | 0 | 8.64 | 2.04 | $1 |
| Affeldt, Jeremy | KC | 49 | 49.2 | 39 | 29 | 56 | 29 | 0 | 2 | 0 | 5.26 | 1.71 | $1 |
| Alfonseca, Antonio | FLO | 33 | 27.1 | 16 | 14 | 29 | 15 | 1 | 1 | 0 | 4.94 | 1.57 | $1 |
| Almanza, Armando | ARZ | 6 | 4 | 2 | 3 | 5 | 1 | 0 | 0 | 0 | 2.25 | 2 | $1 |
| Almanzar, Carlos | TEX | 6 | 5 | 3 | 7 | 10 | 8 | 0 | 0 | 0 | 14.4 | 3.4 | $1 |
| Alvarez, Abe | BOS | 2 | 2.1 | 1 | 0 | 6 | 4 | 0 | 0 | 0 | 15.43 | 2.57 | $1 |
| Anderson, Brian | KC | 6 | 30.2 | 17 | 4 | 39 | 23 | 1 | 2 | 0 | 6.75 | 1.4 | $1 |
| Anderson, Jason | NYY | 3 | 5.2 | 2 | 7 | 4 | 5 | 1 | 0 | 0 | 7.94 | 1.94 | $1 |
| Anderson, Matt | COL | 12 | 10 | 4 | 11 | 19 | 14 | 0 | 0 | 0 | 12.6 | 3 | $1 |
| Aquino, Greg | ARZ | 35 | 31.1 | 34 | 17 | 42 | 27 | 0 | 1 | 1 | 7.76 | 1.88 | $1 |
| Armas, Tony | WAS | 19 | 101.1 | 59 | 54 | 100 | 56 | 7 | 7 | 0 | 4.97 | 1.52 | $1 |
| Astacio, Ezequiel | HOU | 22 | 81 | 66 | 25 | 100 | 51 | 3 | 6 | 0 | 5.67 | 1.54 | $1 |
| Astacio, Pedro | TEX | 12 | 67 | 45 | 11 | 79 | 45 | 2 | 8 | 0 | 6.04 | 1.34 | $1 |
| Atchison, Scott | SEA | 6 | 6.2 | 9 | 1 | 7 | 5 | 0 | 0 | 0 | 6.75 | 1.2 | $1 |
| Aybar, Manuel | NYM | 22 | 25.1 | 27 | 7 | 31 | 17 | 0 | 0 | 0 | 6.04 | 1.5 | $1 |
| Backe, Brandon | HOU | 26 | 149.1 | 97 | 67 | 151 | 79 | 10 | 8 | 0 | 4.76 | 1.46 | $1 |
| Bajenaru, Jeff | CWS | 4 | 4.1 | 3 | 0 | 4 | 3 | 0 | 0 | 0 | 6.23 | 0.92 | $1 |
| Baker, Scott | MIN | 10 | 53.2 | 32 | 14 | 48 | 20 | 3 | 3 | 0 | 3.35 | 1.16 | $1 |
| Baldwin, James | BAL | 28 | 56.2 | 29 | 16 | 54 | 24 | 0 | 2 | 1 | 3.81 | 1.24 | $1 |
| Bartosh, Cliff | CHC | 19 | 19.2 | 15 | 11 | 23 | 12 | 0 | 2 | 0 | 5.49 | 1.73 | $1 |
| Bauer, Rick | BAL | 5 | 8.1 | 5 | 4 | 13 | 9 | 0 | 0 | 0 | 9.72 | 2.04 | $1 |
| Bautista, Denny | KC | 7 | 35.2 | 23 | 17 | 36 | 23 | 2 | 2 | 0 | 5.8 | 1.49 | $1 |
| Bayliss, Jonah | KC | 11 | 11.2 | 10 | 4 | 7 | 6 | 0 | 0 | 0 | 4.63 | 0.94 | $1 |
| Bazardo, Yorman | FLO | 1 | 1.2 | 2 | 2 | 5 | 4 | 0 | 0 | 0 | 21.6 | 4.2 | $1 |
| Bean, Colter | NYY | 1 | 2 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 4.5 | 1.5 | $1 |
| Beimel, Joe | TB | 7 | 11 | 3 | 4 | 15 | 4 | 0 | 0 | 0 | 3.27 | 1.73 | $1 |
| Belisle, Matt | CIN | 60 | 85.2 | 59 | 26 | 101 | 42 | 4 | 8 | 1 | 4.41 | 1.48 | $1 |
| Bell, Heath | NYM | 42 | 46.2 | 43 | 13 | 56 | 29 | 1 | 3 | 0 | 5.59 | 1.48 | $1 |
| Bell, Rob | TB | 8 | 25 | 13 | 12 | 41 | 23 | 1 | 1 | 0 | 8.28 | 2.12 | $1 |
| Bentz, Chad | FLO | 4 | 2 | 0 | 0 | 8 | 7 | 0 | 0 | 0 | 31.5 | 4 | $1 |
| Bergmann, Jay | WAS | 15 | 19.2 | 21 | 11 | 14 | 6 | 2 | 0 | 0 | 2.75 | 1.27 | $1 |
| Bernero, Adam | ATL | 36 | 47 | 37 | 12 | 61 | 34 | 4 | 3 | 0 | 6.51 | 1.55 | $1 |
| Booker, Chris | CIN | 3 | 2 | 2 | 4 | 6 | 7 | 0 | 0 | 0 | 31.5 | 5 | $1 |
| Bootcheck, Christo | ANA | 5 | 18.2 | 8 | 4 | 19 | 7 | 0 | 1 | 1 | 3.38 | 1.23 | $1 |
| Borowski, Joe | TB | 32 | 35.1 | 16 | 11 | 26 | 15 | 1 | 5 | 0 | 3.82 | 1.05 | $1 |
| Borowski, Joe | CHC | 11 | 11 | 11 | 1 | 12 | 8 | 0 | 0 | 0 | 6.55 | 1.18 | $1 |
| Bottalico, Ricky | MLW | 40 | 41.2 | 29 | 19 | 43 | 21 | 2 | 2 | 2 | 4.54 | 1.49 | $1 |
| Bowyer, Travis | MIN | 8 | 9.2 | 12 | 3 | 10 | 6 | 0 | 1 | 0 | 5.59 | 1.34 | $1 |
| Bradford, Chad | BOS | 31 | 23.1 | 10 | 4 | 29 | 10 | 2 | 1 | 0 | 3.86 | 1.41 | $1 |
| Brazelton, Dewon | TB | 20 | 71 | 43 | 60 | 87 | 60 | 1 | 8 | 0 | 7.61 | 2.07 | $1 |
| Breslow, Craig | SD | 14 | 16.1 | 14 | 13 | 15 | 4 | 0 | 0 | 0 | 2.2 | 1.71 | $1 |
| Brito, Eude | PHI | 6 | 22 | 15 | 11 | 20 | 9 | 1 | 2 | 0 | 3.68 | 1.41 | $1 |
| Brocail, Doug | TEX | 61 | 73.1 | 61 | 34 | 90 | 45 | 5 | 3 | 1 | 5.52 | 1.69 | $1 |
| Brooks, Frank | ATL | 1 | 0.1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | $1 |
| Brower, Jim | ATL | 69 | 60.1 | 53 | 32 | 73 | 36 | 3 | 3 | 1 | 5.37 | 1.74 | $1 |
| Broxton, Jonathan | LA | 14 | 13.2 | 22 | 12 | 13 | 9 | 1 | 0 | 0 | 5.93 | 1.83 | $1 |
| Bruney, Brian | ARZ | 47 | 46 | 51 | 35 | 56 | 38 | 1 | 3 | 12 | 7.43 | 1.98 | $1 |
| Bukvich, Ryan | TEX | 4 | 4 | 4 | 6 | 2 | 5 | 0 | 0 | 0 | 11.25 | 2 | $1 |
| Bulger, Jason | ARZ | 9 | 10 | 9 | 5 | 14 | 6 | 1 | 0 | 0 | 5.4 | 1.9 | $1 |
| Bullington, Bryan | PIT | 1 | 1.1 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 13.5 | 1.5 | $1 |
| Bump, Nate | FLO | 31 | 38 | 18 | 12 | 43 | 17 | 0 | 3 | 0 | 4.03 | 1.45 | $1 |
| Burgos, Ambiorix | KC | 59 | 63.1 | 65 | 31 | 60 | 28 | 3 | 5 | 2 | 3.98 | 1.44 | $1 |
| Burns, Mike | HOU | 27 | 31 | 20 | 8 | 29 | 17 | 0 | 0 | 0 | 4.94 | 1.19 | $1 |
| Byrdak, Tim | BAL | 41 | 26.2 | 31 | 21 | 27 | 12 | 0 | 1 | 1 | 4.05 | 1.8 | $1 |
| Cabrera, Fernando | CLE | 15 | 30.2 | 29 | 11 | 24 | 5 | 2 | 1 | 0 | 1.47 | 1.14 | $1 |
| Cali, Carmen | STL | 6 | 6 | 5 | 6 | 10 | 7 | 0 | 0 | 0 | 10.5 | 2.67 | $1 |
| Camp, Shawn | KC | 29 | 49 | 28 | 13 | 69 | 35 | 1 | 4 | 0 | 6.43 | 1.67 | $1 |
| Campillo, Jorge | SEA | 2 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | $1 |
| Capellan, Jose | MLW | 17 | 15.2 | 14 | 5 | 17 | 5 | 1 | 1 | 0 | 2.87 | 1.4 | $1 |
| Capps, Matt | PIT | 4 | 4 | 3 | 0 | 5 | 2 | 0 | 0 | 0 | 4.5 | 1.25 | $1 |
| Carlyle, Buddy | LA | 10 | 14 | 13 | 4 | 16 | 13 | 0 | 0 | 0 | 8.36 | 1.43 | $1 |
| Carrasco, Dan | KC | 21 | 114.2 | 49 | 51 | 129 | 61 | 6 | 8 | 0 | 4.79 | 1.57 | $1 |
| Carter, Lance | TB | 39 | 57 | 22 | 15 | 61 | 31 | 1 | 2 | 1 | 4.89 | 1.33 | $1 |
| Carvajal, Marcos | COL | 39 | 53 | 47 | 21 | 52 | 30 | 0 | 2 | 0 | 5.09 | 1.38 | $1 |
| Cassidy, Scott | SD | 10 | 12.1 | 12 | 3 | 15 | 9 | 1 | 1 | 0 | 6.57 | 1.46 | $1 |
| Cassidy, Scott | BOS | 1 | 0.2 | 0 | 0 | 4 | 3 | 0 | 0 | 0 | 40.5 | 6 | $1 |
| Castillo, Frank | FLO | 1 | 4.1 | 4 | 5 | 4 | 5 | 0 | 1 | 0 | 10.38 | 2.08 | $1 |
| Cerda, Jaime | KC | 20 | 19 | 18 | 11 | 21 | 14 | 1 | 4 | 0 | 6.63 | 1.68 | $1 |
| Chacon, Shawn | COL | 13 | 72.2 | 39 | 36 | 69 | 33 | 1 | 7 | 0 | 4.09 | 1.44 | $1 |
| Childers, Matt | ATL | 3 | 4 | 2 | 3 | 5 | 2 | 0 | 0 | 0 | 4.5 | 2 | $1 |
| Choate, Randy | ARZ | 8 | 7 | 4 | 5 | 8 | 7 | 0 | 0 | 0 | 9 | 1.86 | $1 |
| Christiansen, Jaso | SF | 56 | 42 | 17 | 15 | 48 | 25 | 6 | 1 | 0 | 5.36 | 1.5 | $1 |
| Christiansen, Jaso | ANA | 12 | 3.2 | 4 | 2 | 7 | 1 | 0 | 0 | 0 | 2.45 | 2.45 | $1 |
| Chulk, Vinnie | TOR | 62 | 72 | 39 | 26 | 68 | 31 | 0 | 1 | 0 | 3.88 | 1.31 | $1 |
| Coffey, Todd | CIN | 57 | 58 | 26 | 11 | 84 | 29 | 4 | 1 | 1 | 4.5 | 1.64 | $1 |
| Colome, Jesus | TB | 36 | 45.1 | 28 | 18 | 54 | 23 | 2 | 3 | 0 | 4.57 | 1.59 | $1 |
| Colon, Roman | ATL | 23 | 44.1 | 30 | 14 | 47 | 26 | 1 | 5 | 0 | 5.28 | 1.38 | $1 |
| Colon, Roman | DET | 12 | 25 | 17 | 7 | 35 | 17 | 1 | 1 | 0 | 6.12 | 1.68 | $1 |
| Cooper, Brian | SF | 8 | 17.2 | 7 | 8 | 15 | 6 | 0 | 1 | 0 | 3.06 | 1.3 | $1 |
| Corcoran, Tim | TB | 10 | 22.2 | 13 | 12 | 19 | 15 | 0 | 0 | 0 | 5.96 | 1.37 | $1 |
| Cormier, Lance | ARZ | 67 | 79.1 | 63 | 43 | 86 | 45 | 7 | 3 | 0 | 5.11 | 1.63 | $1 |
| Cormier, Rheal | PHI | 57 | 47.1 | 34 | 16 | 56 | 31 | 4 | 2 | 0 | 5.89 | 1.52 | $1 |
| Correia, Kevin | SF | 16 | 58.1 | 44 | 31 | 61 | 30 | 2 | 5 | 0 | 4.63 | 1.58 | $1 |
| Creek, Doug | DET | 20 | 22.1 | 18 | 7 | 27 | 17 | 0 | 0 | 0 | 6.85 | 1.52 | $1 |
| Crowell, Jim | FLO | 4 | 3.1 | 2 | 0 | 10 | 8 | 0 | 0 | 0 | 21.6 | 3 | $1 |
| Cruz, Juan | OAK | 28 | 32.2 | 34 | 22 | 38 | 27 | 0 | 3 | 0 | 7.44 | 1.84 | $1 |
| Darensbourg, Vic | DET | 22 | 22.1 | 9 | 7 | 24 | 7 | 1 | 1 | 0 | 2.82 | 1.39 | $1 |
| Davies, Kyle | ATL | 21 | 87.2 | 62 | 49 | 98 | 48 | 7 | 6 | 0 | 4.93 | 1.68 | $1 |
| Davis, Jason | CLE | 11 | 40.1 | 32 | 20 | 44 | 21 | 4 | 2 | 0 | 4.69 | 1.59 | $1 |
| Davis, Kane | MLW | 15 | 16.2 | 11 | 10 | 10 | 5 | 1 | 1 | 0 | 2.7 | 1.2 | $1 |
| Day, Zach | COL | 17 | 47.1 | 23 | 32 | 61 | 36 | 1 | 3 | 0 | 6.85 | 1.96 | $1 |
| De La Rosa, Jorge | MLW | 38 | 42.1 | 42 | 38 | 48 | 21 | 2 | 2 | 0 | 4.46 | 2.03 | $1 |
| De Los Santos, Val | FLO | 27 | 22 | 16 | 12 | 25 | 15 | 1 | 2 | 0 | 6.14 | 1.68 | $1 |
| De Paula, Julio | NYY | 3 | 6.2 | 3 | 3 | 8 | 6 | 0 | 0 | 0 | 8.1 | 1.65 | $1 |
| DeJean, Mike | COL | 66 | 62.1 | 52 | 30 | 62 | 31 | 5 | 4 | 0 | 4.48 | 1.48 | $1 |
| Delcarmen, Manny | BOS | 10 | 9 | 9 | 7 | 8 | 3 | 0 | 0 | 0 | 3 | 1.67 | $1 |
| Demaria, Chris | KC | 8 | 9 | 11 | 5 | 14 | 9 | 1 | 0 | 0 | 9 | 2.11 | $1 |
| Dessens, Elmer | LA | 28 | 65.2 | 37 | 19 | 63 | 26 | 1 | 2 | 0 | 3.56 | 1.25 | $1 |
| Devine, Joey | ATL | 5 | 5 | 3 | 5 | 6 | 7 | 0 | 1 | 0 | 12.6 | 2.2 | $1 |
| Dickey, R.A. | TEX | 9 | 29.2 | 15 | 17 | 29 | 22 | 1 | 2 | 0 | 6.67 | 1.55 | $1 |
| DiNardo, Lenny | BOS | 8 | 14.2 | 15 | 5 | 13 | 3 | 0 | 1 | 0 | 1.84 | 1.23 | $1 |
| Dingman, Craig | DET | 34 | 32 | 24 | 9 | 30 | 13 | 2 | 3 | 4 | 3.66 | 1.22 | $1 |
| Dohmann, Scott | COL | 32 | 31 | 35 | 19 | 33 | 21 | 2 | 1 | 0 | 6.1 | 1.68 | $1 |
| Dominguez, Juan | TEX | 22 | 70.1 | 45 | 25 | 78 | 33 | 4 | 6 | 0 | 4.22 | 1.46 | $1 |
| Douglass, Sean | DET | 18 | 87.1 | 55 | 33 | 92 | 54 | 5 | 5 | 0 | 5.56 | 1.43 | $1 |
| Driskill, Travis | HOU | 1 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | $1 |
| DuBose, Eric | BAL | 15 | 29.1 | 17 | 19 | 28 | 18 | 2 | 3 | 0 | 5.52 | 1.6 | $1 |
| Duckworth, Brandon | HOU | 7 | 16.1 | 10 | 7 | 24 | 20 | 0 | 1 | 0 | 11.02 | 1.9 | $1 |
| Eischen, Joey | WAS | 57 | 36.1 | 30 | 19 | 34 | 13 | 2 | 1 | 0 | 3.22 | 1.46 | $1 |
| Eldred, Cal | STL | 31 | 37 | 29 | 18 | 35 | 9 | 1 | 0 | 0 | 2.19 | 1.43 | $1 |
| Embree, Alan | NYY | 67 | 52 | 38 | 14 | 62 | 44 | 2 | 5 | 1 | 7.62 | 1.46 | $1 |
| Erickson, Scott | LA | 19 | 55.1 | 15 | 25 | 62 | 37 | 1 | 4 | 0 | 6.02 | 1.57 | $1 |
| Esposito, Mike | COL | 3 | 14.2 | 5 | 9 | 21 | 11 | 0 | 2 | 0 | 6.75 | 2.05 | $1 |
| Estes, Shawn | ARZ | 21 | 123.2 | 63 | 45 | 132 | 66 | 7 | 8 | 0 | 4.8 | 1.43 | $1 |
| Etherton, Seth | OAK | 3 | 17.2 | 10 | 5 | 16 | 13 | 1 | 1 | 0 | 6.62 | 1.19 | $1 |
| Eveland, Dana | MLW | 27 | 31.2 | 23 | 18 | 40 | 21 | 1 | 1 | 1 | 5.97 | 1.83 | $1 |
| Falkenborg, Brian | SD | 10 | 11 | 10 | 5 | 17 | 10 | 0 | 0 | 0 | 8.18 | 2 | $1 |
| Fassero, Jeff | SF | 48 | 91 | 60 | 31 | 92 | 41 | 4 | 7 | 0 | 4.05 | 1.35 | $1 |
| Feldman, Scott | TEX | 8 | 9.1 | 4 | 2 | 9 | 1 | 0 | 1 | 0 | 0.96 | 1.18 | $1 |
| Field, Nate | KC | 7 | 6.2 | 4 | 5 | 13 | 7 | 0 | 0 | 0 | 9.45 | 2.7 | $1 |
| Flores, Ron | OAK | 11 | 8.2 | 6 | 0 | 8 | 1 | 0 | 0 | 0 | 1.04 | 0.92 | $1 |
| Floyd, Gavin | PHI | 7 | 26 | 17 | 16 | 30 | 29 | 1 | 2 | 0 | 10.04 | 1.77 | $1 |
| Fogg, Josh | PIT | 34 | 169.1 | 85 | 53 | 196 | 95 | 6 | 11 | 0 | 5.05 | 1.47 | $1 |
| Foppert, Jesse | SF | 3 | 10.1 | 6 | 13 | 11 | 6 | 0 | 0 | 0 | 5.23 | 2.32 | $1 |
| Foster, John | ATL | 62 | 34.2 | 32 | 19 | 27 | 16 | 4 | 2 | 1 | 4.15 | 1.33 | $1 |
| Fox, Chad | CHC | 11 | 8 | 11 | 8 | 8 | 6 | 0 | 0 | 1 | 6.75 | 2 | $1 |
| Francis, Jeff | COL | 33 | 183.2 | 128 | 70 | 228 | 116 | 14 | 12 | 0 | 5.68 | 1.62 | $1 |
| Franco, John | HOU | 31 | 15 | 16 | 9 | 23 | 12 | 0 | 1 | 0 | 7.2 | 2.13 | $1 |
| Franklin, Wayne | NYY | 13 | 12.2 | 10 | 8 | 11 | 9 | 0 | 1 | 0 | 6.39 | 1.5 | $1 |
| Gallo, Mike | HOU | 36 | 20.1 | 12 | 10 | 18 | 6 | 0 | 1 | 0 | 2.66 | 1.38 | $1 |
| Garcia, Jairo | OAK | 3 | 3 | 1 | 1 | 2 | 1 | 0 | 0 | 0 | 3 | 1 | $1 |
| Gardner, Lee | TB | 5 | 7.1 | 4 | 2 | 12 | 4 | 0 | 0 | 0 | 4.91 | 1.91 | $1 |
| Gassner, Dave | MIN | 2 | 7.2 | 2 | 1 | 9 | 5 | 1 | 0 | 0 | 5.87 | 1.3 | $1 |
| Gaudin, Chad | TOR | 5 | 13 | 12 | 6 | 31 | 19 | 1 | 3 | 0 | 13.15 | 2.85 | $1 |
| Geary, Geoff | PHI | 40 | 58 | 42 | 21 | 54 | 24 | 2 | 1 | 0 | 3.72 | 1.29 | $1 |
| German, Franklyn | DET | 58 | 59 | 38 | 34 | 63 | 24 | 4 | 0 | 1 | 3.66 | 1.64 | $1 |
| Ginter, Matt | DET | 14 | 35 | 15 | 9 | 49 | 24 | 0 | 1 | 0 | 6.17 | 1.66 | $1 |
| Glover, Gary | MLW | 15 | 64.2 | 58 | 20 | 74 | 40 | 5 | 4 | 0 | 5.57 | 1.45 | $1 |
| Glynn, Ryan | OAK | 5 | 17 | 15 | 7 | 24 | 13 | 0 | 4 | 0 | 6.88 | 1.82 | $1 |
| Gobble, Jimmy | KC | 28 | 53.2 | 38 | 30 | 64 | 34 | 1 | 1 | 0 | 5.7 | 1.75 | $1 |
| Gonzalez, Edgar | ARZ | 1 | 0.1 | 1 | 2 | 2 | 4 | 0 | 0 | 0 | 108 | 12 | $1 |
| Gonzalez, Jeremi | BOS | 28 | 56 | 28 | 16 | 64 | 38 | 2 | 1 | 0 | 6.11 | 1.43 | $1 |
| Good, Andy | DET | 2 | 5 | 7 | 1 | 4 | 3 | 0 | 0 | 0 | 5.4 | 1 | $1 |
| Gorzelanny, Tom | PIT | 3 | 6 | 3 | 3 | 10 | 8 | 0 | 1 | 0 | 12 | 2.17 | $1 |
| Gosling, Mike | ARZ | 13 | 32.1 | 14 | 19 | 40 | 16 | 0 | 3 | 0 | 4.45 | 1.82 | $1 |
| Grabow, John | PIT | 63 | 52 | 42 | 25 | 46 | 28 | 2 | 3 | 0 | 4.85 | 1.37 | $1 |
| Graman, Alex | NYY | 2 | 1.1 | 0 | 2 | 3 | 2 | 0 | 0 | 0 | 13.5 | 3.75 | $1 |
| Gregg, Kevin | ANA | 33 | 64.1 | 52 | 29 | 70 | 36 | 1 | 2 | 0 | 5.04 | 1.54 | $1 |
| Greisinger, Seth | ATL | 1 | 5 | 2 | 1 | 7 | 2 | 0 | 0 | 0 | 3.6 | 1.6 | $1 |
| Grilli, Jason | DET | 3 | 16 | 5 | 6 | 14 | 6 | 1 | 1 | 0 | 3.38 | 1.25 | $1 |
| Grimsley, Jason | BAL | 22 | 22 | 10 | 9 | 24 | 14 | 1 | 2 | 0 | 5.73 | 1.5 | $1 |
| Groom, Buddy | ARZ | 23 | 15.1 | 7 | 5 | 19 | 8 | 0 | 1 | 1 | 4.7 | 1.57 | $1 |
| Groom, Buddy | NYY | 24 | 25.2 | 13 | 7 | 32 | 14 | 1 | 0 | 0 | 4.91 | 1.52 | $1 |
| Gryboski, Kevin | ATL | 31 | 21.1 | 8 | 12 | 24 | 7 | 0 | 0 | 0 | 2.95 | 1.69 | $1 |
| Gryboski, Kevin | TEX | 11 | 9.2 | 2 | 8 | 17 | 12 | 1 | 1 | 0 | 11.17 | 2.59 | $1 |
| Guerrier, Matt | MIN | 43 | 71.2 | 46 | 24 | 71 | 27 | 0 | 3 | 0 | 3.39 | 1.33 | $1 |
| Guthrie, Jeremy | CLE | 1 | 6 | 3 | 2 | 9 | 4 | 0 | 0 | 0 | 6 | 1.83 | $1 |
| Halama, John | WAS | 10 | 21.1 | 11 | 8 | 23 | 11 | 0 | 3 | 0 | 4.64 | 1.45 | $1 |
| Halama, John | BOS | 30 | 43.2 | 26 | 9 | 56 | 30 | 1 | 1 | 0 | 6.18 | 1.49 | $1 |
| Halsey, Brad | ARZ | 28 | 160 | 82 | 39 | 191 | 82 | 8 | 12 | 0 | 4.61 | 1.44 | $1 |
| Hamulack, Tim | NYM | 6 | 2.1 | 2 | 1 | 7 | 6 | 0 | 0 | 0 | 23.14 | 3.43 | $1 |
| Hancock, Joshua | CIN | 11 | 14 | 5 | 1 | 11 | 3 | 1 | 0 | 0 | 1.93 | 0.86 | $1 |
| Hansen, Craig | BOS | 4 | 3 | 3 | 1 | 6 | 2 | 0 | 0 | 0 | 6 | 2.33 | $1 |
| Harikkala, Tim | OAK | 8 | 12.2 | 7 | 4 | 16 | 9 | 0 | 0 | 0 | 6.39 | 1.58 | $1 |
| Harper, Travis | TB | 52 | 73.1 | 40 | 24 | 88 | 55 | 4 | 6 | 0 | 6.75 | 1.53 | $1 |
| Harris, Jeff | SEA | 11 | 53.2 | 25 | 20 | 48 | 25 | 2 | 5 | 0 | 4.19 | 1.27 | $1 |
| Harville, Chad | HOU | 37 | 38.1 | 33 | 24 | 36 | 19 | 0 | 2 | 0 | 4.46 | 1.57 | $1 |
| Harville, Chad | BOS | 8 | 7 | 3 | 3 | 7 | 5 | 0 | 1 | 0 | 6.43 | 1.43 | $1 |
| Hasegawa, Shigetos | SEA | 46 | 66.2 | 30 | 16 | 66 | 31 | 1 | 3 | 0 | 4.19 | 1.23 | $1 |
| Henn, Sean | NYY | 3 | 11.1 | 3 | 11 | 18 | 14 | 0 | 3 | 0 | 11.12 | 2.56 | $1 |
| Hennessey, Brad | SF | 21 | 118.1 | 64 | 52 | 127 | 61 | 5 | 8 | 0 | 4.64 | 1.51 | $1 |
| Heredia, Felix | NYM | 3 | 2.2 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0.75 | $1 |
| Herges, Matt | ARZ | 28 | 29 | 9 | 12 | 35 | 23 | 1 | 1 | 0 | 7.14 | 1.62 | $1 |
| Hernandez, Runelvy | KC | 29 | 159.2 | 88 | 70 | 172 | 98 | 8 | 14 | 0 | 5.52 | 1.52 | $1 |
| Hill, Rich | CHC | 10 | 23.2 | 21 | 17 | 25 | 24 | 0 | 2 | 0 | 9.13 | 1.77 | $1 |
| Horgan, Joe | WAS | 8 | 6 | 5 | 4 | 19 | 14 | 0 | 0 | 0 | 21 | 3.83 | $1 |
| Houlton, Dennis | LA | 35 | 129 | 90 | 52 | 145 | 74 | 6 | 9 | 0 | 5.16 | 1.53 | $1 |
| Howell, J.P. | KC | 15 | 72.2 | 54 | 39 | 73 | 50 | 3 | 5 | 0 | 6.19 | 1.54 | $1 |
| Hudson, Luke | CIN | 19 | 84.2 | 53 | 50 | 83 | 60 | 6 | 9 | 0 | 6.38 | 1.57 | $1 |
| Hughes, Travis | WAS | 14 | 13 | 8 | 8 | 18 | 8 | 1 | 1 | 0 | 5.54 | 2 | $1 |
| Ishii, Kazuhisa | NYM | 19 | 91 | 53 | 49 | 87 | 52 | 3 | 9 | 0 | 5.14 | 1.49 | $1 |
| Jackson, Edwin | LA | 7 | 28.2 | 13 | 17 | 31 | 20 | 2 | 2 | 0 | 6.28 | 1.67 | $1 |
| James, Chuck | ATL | 2 | 5.2 | 5 | 3 | 4 | 1 | 0 | 0 | 0 | 1.59 | 1.24 | $1 |
| Jarvis, Kevin | STL | 4 | 3.1 | 2 | 3 | 3 | 5 | 0 | 1 | 0 | 13.5 | 1.8 | $1 |
| Jennings, Jason | COL | 20 | 122 | 75 | 62 | 130 | 68 | 6 | 9 | 0 | 5.02 | 1.57 | $1 |
| Jensen, Ryan | KC | 9 | 25.1 | 18 | 7 | 31 | 20 | 3 | 2 | 0 | 7.11 | 1.5 | $1 |
| Johnson, Josh | FLO | 4 | 12.1 | 10 | 10 | 11 | 5 | 0 | 0 | 0 | 3.65 | 1.7 | $1 |
| Johnson, Tyler | STL | 5 | 2.2 | 4 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 2.25 | $1 |
| Johnston, Mike | PIT | 1 | 1 | 2 | 0 | 4 | 4 | 0 | 0 | 0 | 36 | 4 | $1 |
| Jones, Greg | ANA | 6 | 5.1 | 6 | 2 | 7 | 4 | 0 | 0 | 0 | 6.75 | 1.69 | $1 |
| Journell, Jimmy | STL | 5 | 4.1 | 5 | 5 | 6 | 5 | 0 | 1 | 0 | 10.38 | 2.54 | $1 |
| Karnuth, Jason | DET | 3 | 1.2 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 5.4 | 1.2 | $1 |
| Karsay, Steve | TEX | 20 | 21.2 | 14 | 7 | 36 | 17 | 0 | 1 | 0 | 7.06 | 1.98 | $1 |
| Keisler, Randy | CIN | 24 | 56 | 43 | 28 | 64 | 39 | 2 | 1 | 0 | 6.27 | 1.64 | $1 |
| Kennedy, Joe | COL | 16 | 92 | 52 | 44 | 128 | 72 | 4 | 8 | 0 | 7.04 | 1.87 | $1 |
| Kensing, Logan | FLO | 3 | 5.2 | 4 | 3 | 11 | 7 | 0 | 0 | 0 | 11.12 | 2.47 | $1 |
| Kida, Masao | SEA | 1 | 2 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 4.5 | 1 | $1 |
| Kim, Byung-Hyun | COL | 40 | 148 | 115 | 71 | 156 | 80 | 5 | 12 | 0 | 4.86 | 1.53 | $1 |
| Kim, Sun-Woo | COL | 24 | 82.2 | 55 | 21 | 97 | 45 | 6 | 3 | 0 | 4.9 | 1.43 | $1 |
| Kinney, Matt | SF | 5 | 12 | 3 | 6 | 18 | 8 | 2 | 0 | 0 | 6 | 2 | $1 |
| Kolb, Danny | ATL | 65 | 57.2 | 39 | 29 | 78 | 38 | 3 | 8 | 11 | 5.93 | 1.86 | $1 |
| Koo, Dae-Sung | NYM | 33 | 23 | 23 | 13 | 22 | 10 | 0 | 0 | 0 | 3.91 | 1.52 | $1 |
| Koplove, Mike | ARZ | 44 | 49.2 | 28 | 20 | 48 | 28 | 2 | 1 | 0 | 5.07 | 1.37 | $1 |
| Koronka, John | CHC | 4 | 15.2 | 10 | 8 | 19 | 13 | 1 | 2 | 0 | 7.47 | 1.72 | $1 |
| Kuo, Hong-Chih | LA | 9 | 5.1 | 10 | 5 | 5 | 4 | 0 | 1 | 0 | 6.75 | 1.88 | $1 |
| League, Brandon | TOR | 20 | 35.2 | 17 | 20 | 42 | 26 | 1 | 0 | 0 | 6.56 | 1.74 | $1 |
| Ledezma, Wil | DET | 10 | 49.2 | 30 | 24 | 61 | 39 | 2 | 4 | 0 | 7.07 | 1.71 | $1 |
| Lehr, Justin | MLW | 23 | 34.2 | 23 | 18 | 32 | 15 | 1 | 1 | 0 | 3.89 | 1.44 | $1 |
| Leicester, Jon | CHC | 6 | 9 | 7 | 9 | 11 | 9 | 0 | 2 | 0 | 9 | 2.22 | $1 |
| Leiter, Al | FLO | 17 | 80 | 52 | 60 | 88 | 59 | 3 | 7 | 0 | 6.64 | 1.85 | $1 |
| Lerew, Anthony | ATL | 7 | 8 | 5 | 5 | 9 | 5 | 0 | 0 | 0 | 5.63 | 1.75 | $1 |
| Levine, Al | SF | 9 | 10.1 | 4 | 4 | 16 | 11 | 0 | 0 | 0 | 9.58 | 1.94 | $1 |
| Ligtenberg, Kerry | ARZ | 7 | 9.2 | 5 | 4 | 16 | 15 | 0 | 0 | 0 | 13.97 | 2.07 | $1 |
| Lima, Jose | KC | 32 | 168.2 | 80 | 61 | 219 | 131 | 5 | 16 | 0 | 6.99 | 1.66 | $1 |
| Liriano, Francisco | MIN | 6 | 23.2 | 33 | 7 | 19 | 15 | 1 | 2 | 0 | 5.7 | 1.1 | $1 |
| Liriano, Pedro | PHI | 5 | 7.2 | 6 | 6 | 10 | 9 | 0 | 0 | 0 | 10.57 | 2.09 | $1 |
| Lopez, Aquilino | PHI | 11 | 16.2 | 22 | 7 | 16 | 4 | 0 | 1 | 0 | 2.16 | 1.38 | $1 |
| Lopez, Javier | ARZ | 32 | 16.1 | 12 | 11 | 26 | 20 | 1 | 1 | 2 | 11.02 | 2.27 | $1 |
| Lyon, Brandon | ARZ | 32 | 29.1 | 17 | 10 | 44 | 21 | 0 | 2 | 14 | 6.44 | 1.84 | $1 |
| Madritsch, Bobby | SEA | 1 | 4.1 | 1 | 1 | 4 | 3 | 0 | 1 | 0 | 6.23 | 1.15 | $1 |
| Mahay, Ron | TEX | 30 | 35.2 | 30 | 16 | 47 | 27 | 0 | 2 | 1 | 6.81 | 1.77 | $1 |
| Maine, John | BAL | 10 | 40 | 24 | 24 | 39 | 28 | 2 | 3 | 0 | 6.3 | 1.58 | $1 |
| Mantei, Matt | BOS | 34 | 26.1 | 22 | 24 | 23 | 19 | 1 | 0 | 0 | 6.49 | 1.78 | $1 |
| Marcum, Shaun | TOR | 5 | 8 | 4 | 4 | 6 | 0 | 0 | 0 | 0 | 0 | 1.25 | $1 |
| Martin, Tom | ATL | 4 | 2.1 | 0 | 2 | 6 | 5 | 0 | 0 | 0 | 19.29 | 3.43 | $1 |
| Matthews, Mike | NYM | 6 | 5 | 2 | 4 | 9 | 6 | 1 | 0 | 0 | 10.8 | 2.6 | $1 |
| May, Darrell | SD | 22 | 59.1 | 32 | 20 | 73 | 37 | 1 | 3 | 0 | 5.61 | 1.57 | $1 |
| May, Darrell | NYY | 2 | 7 | 3 | 3 | 14 | 13 | 0 | 1 | 0 | 16.71 | 2.43 | $1 |
| Mays, Joe | MIN | 31 | 156 | 59 | 41 | 203 | 98 | 6 | 10 | 0 | 5.65 | 1.56 | $1 |
| McBride, Macay | ATL | 23 | 14 | 22 | 7 | 18 | 9 | 1 | 0 | 1 | 5.79 | 1.79 | $1 |
| McClung, Seth | TB | 34 | 109.1 | 92 | 62 | 106 | 80 | 7 | 11 | 0 | 6.59 | 1.54 | $1 |
| McGowan, Dustin | TOR | 13 | 45.1 | 34 | 17 | 49 | 32 | 1 | 3 | 0 | 6.35 | 1.46 | $1 |
| Meadows, Brian | PIT | 65 | 74.2 | 44 | 21 | 84 | 38 | 3 | 1 | 0 | 4.58 | 1.41 | $1 |
| Mecir, Jim | FLO | 52 | 43.1 | 34 | 17 | 39 | 15 | 1 | 4 | 0 | 3.12 | 1.29 | $1 |
| Mendoza, Ramiro | NYY | 1 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 18 | 2 | $1 |
| Meredith, Olise | BOS | 3 | 2.1 | 0 | 4 | 6 | 7 | 0 | 0 | 0 | 27 | 4.29 | $1 |
| Messenger, Randy | FLO | 29 | 37 | 29 | 30 | 39 | 22 | 0 | 0 | 0 | 5.35 | 1.86 | $1 |
| Miceli, Dan | COL | 19 | 18.1 | 19 | 13 | 19 | 12 | 1 | 2 | 0 | 5.89 | 1.75 | $1 |
| Miller, Justin | TOR | 1 | 2.1 | 2 | 0 | 5 | 4 | 0 | 0 | 0 | 15.43 | 2.14 | $1 |
| Miller, Trever | TB | 61 | 44.1 | 35 | 29 | 45 | 20 | 2 | 2 | 0 | 4.06 | 1.67 | $1 |
| Milton, Eric | CIN | 34 | 186.1 | 123 | 52 | 237 | 134 | 8 | 15 | 0 | 6.47 | 1.55 | $1 |
| Mitre, Sergio | CHC | 21 | 60.1 | 37 | 23 | 62 | 36 | 2 | 5 | 0 | 5.37 | 1.41 | $1 |
| Moehler, Brian | FLO | 37 | 158.1 | 95 | 42 | 198 | 80 | 6 | 12 | 0 | 4.55 | 1.52 | $1 |
| Mulholland, Terry | MIN | 49 | 59 | 18 | 17 | 61 | 28 | 0 | 2 | 0 | 4.27 | 1.32 | $1 |
| Munter, Scott | SF | 45 | 38.2 | 11 | 12 | 40 | 11 | 2 | 0 | 0 | 2.56 | 1.34 | $1 |
| Myers, Mike | BOS | 65 | 37.1 | 21 | 13 | 30 | 13 | 3 | 1 | 0 | 3.13 | 1.15 | $1 |
| Nageotte, Clint | SEA | 3 | 4 | 1 | 1 | 6 | 3 | 0 | 0 | 0 | 6.75 | 1.75 | $1 |
| Neal, Blaine | COL | 11 | 14.2 | 8 | 9 | 20 | 10 | 1 | 2 | 0 | 6.14 | 1.98 | $1 |
| Neal, Blaine | BOS | 8 | 8 | 3 | 3 | 15 | 8 | 0 | 1 | 0 | 9 | 2.25 | $1 |
| Nelson, Jeff | SEA | 49 | 36.2 | 34 | 22 | 32 | 16 | 1 | 3 | 1 | 3.93 | 1.47 | $1 |
| Nippert, Dustin | ARZ | 3 | 14.2 | 11 | 13 | 10 | 9 | 1 | 0 | 0 | 5.52 | 1.57 | $1 |
| Nitkowski, C.J. | WAS | 7 | 3.1 | 2 | 2 | 5 | 3 | 0 | 0 | 0 | 8.1 | 2.1 | $1 |
| Nomo, Hideo | TB | 19 | 100.2 | 59 | 51 | 127 | 81 | 5 | 8 | 0 | 7.24 | 1.77 | $1 |
| Novoa, Roberto | CHC | 49 | 44.2 | 47 | 25 | 47 | 22 | 4 | 5 | 0 | 4.43 | 1.61 | $1 |
| Nunez, Franklin | TB | 5 | 5 | 2 | 4 | 5 | 6 | 1 | 0 | 0 | 10.8 | 1.8 | $1 |
| Nunez, Leo | KC | 41 | 53.2 | 32 | 18 | 73 | 45 | 3 | 2 | 0 | 7.55 | 1.7 | $1 |
| Obermueller, Wes | MLW | 23 | 65 | 33 | 36 | 74 | 38 | 1 | 4 | 0 | 5.26 | 1.69 | $1 |
| Olsen, Kevin | FLO | 5 | 20.1 | 21 | 10 | 21 | 9 | 1 | 1 | 0 | 3.98 | 1.52 | $1 |
| Ortiz, Ramon | CIN | 30 | 171.1 | 96 | 51 | 206 | 102 | 9 | 11 | 0 | 5.36 | 1.5 | $1 |
| Ortiz, Russ | ARZ | 22 | 115 | 46 | 65 | 147 | 88 | 5 | 11 | 0 | 6.89 | 1.84 | $1 |
| Orvella, Chad | TB | 37 | 50 | 43 | 23 | 47 | 20 | 3 | 3 | 1 | 3.6 | 1.4 | $1 |
| Osoria, Franquelis | LA | 24 | 29.2 | 15 | 8 | 28 | 13 | 0 | 2 | 0 | 3.94 | 1.21 | $1 |
| Osuna, Antonio | WAS | 4 | 2.1 | 0 | 7 | 9 | 11 | 0 | 0 | 0 | 42.43 | 6.86 | $1 |
| Oxspring, Chris | SD | 5 | 12 | 11 | 6 | 9 | 5 | 0 | 0 | 0 | 3.75 | 1.25 | $1 |
| Padilla, Vicente | PHI | 27 | 147 | 103 | 74 | 146 | 77 | 9 | 12 | 0 | 4.71 | 1.5 | $1 |
| Papelbon, Jon | BOS | 17 | 34 | 34 | 17 | 33 | 10 | 3 | 1 | 0 | 2.65 | 1.47 | $1 |
| Park, Chan Ho | TEX | 20 | 109.2 | 80 | 54 | 130 | 69 | 8 | 5 | 0 | 5.66 | 1.68 | $1 |
| Park, Chan Ho | SD | 10 | 45.2 | 33 | 26 | 50 | 30 | 4 | 3 | 0 | 5.91 | 1.66 | $1 |
| Parrish, John | BAL | 14 | 17.1 | 25 | 17 | 19 | 6 | 1 | 0 | 0 | 3.12 | 2.08 | $1 |
| Penn, Hayden | BAL | 8 | 38.1 | 18 | 21 | 46 | 27 | 3 | 2 | 0 | 6.34 | 1.75 | $1 |
| Peralta, Joel | ANA | 28 | 34.2 | 30 | 14 | 28 | 15 | 1 | 0 | 0 | 3.89 | 1.21 | $1 |
| Perisho, Matt | FLO | 24 | 14 | 10 | 11 | 12 | 3 | 2 | 0 | 0 | 1.93 | 1.64 | $1 |
| Perisho, Matt | BOS | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | $1 |
| Phelps, Travis | MLW | 29 | 23.1 | 14 | 12 | 25 | 12 | 0 | 2 | 1 | 4.63 | 1.59 | $1 |
| Ponson, Sidney | BAL | 23 | 130.1 | 68 | 48 | 177 | 90 | 7 | 11 | 0 | 6.21 | 1.73 | $1 |
| Powell, Jay | ATL | 5 | 3.1 | 1 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 1.5 | $1 |
| Prinz, Bret | ANA | 3 | 3 | 1 | 1 | 4 | 1 | 0 | 1 | 0 | 3 | 1.67 | $1 |
| Proctor, Scott | NYY | 29 | 44.2 | 36 | 17 | 46 | 30 | 1 | 0 | 0 | 6.04 | 1.41 | $1 |
| Puffer, Brandon | SF | 3 | 7 | 1 | 2 | 9 | 8 | 0 | 0 | 0 | 10.29 | 1.57 | $1 |
| Pulsipher, Bill | STL | 5 | 4 | 1 | 2 | 5 | 3 | 0 | 0 | 0 | 6.75 | 1.75 | $1 |
| Quantrill, Paul | FLO | 28 | 37 | 25 | 7 | 45 | 17 | 1 | 2 | 0 | 4.14 | 1.41 | $1 |
| Quantrill, Paul | NYY | 22 | 32 | 11 | 7 | 48 | 24 | 1 | 0 | 0 | 6.75 | 1.72 | $1 |
| Rakers, Aaron | BAL | 10 | 13.2 | 11 | 3 | 11 | 5 | 1 | 0 | 0 | 3.29 | 1.02 | $1 |
| Ramirez, Elizardo | CIN | 6 | 22.1 | 9 | 10 | 33 | 21 | 0 | 3 | 0 | 8.46 | 1.93 | $1 |
| Ramirez, Erasmo | TEX | 16 | 23 | 6 | 3 | 24 | 10 | 0 | 0 | 0 | 3.91 | 1.17 | $1 |
| Ramirez, Horacio | ATL | 33 | 202.1 | 80 | 67 | 214 | 104 | 11 | 9 | 0 | 4.63 | 1.39 | $1 |
| Rasner, Darrell | WAS | 5 | 7.1 | 4 | 2 | 5 | 3 | 0 | 1 | 0 | 3.68 | 0.95 | $1 |
| Ray, Chris | BAL | 41 | 40.2 | 43 | 18 | 34 | 12 | 1 | 3 | 0 | 2.66 | 1.28 | $1 |
| Reames, Britt | OAK | 2 | 5.2 | 4 | 2 | 10 | 6 | 0 | 0 | 0 | 9.53 | 2.12 | $1 |
| Redding, Tim | NYY | 1 | 1 | 2 | 4 | 4 | 6 | 0 | 1 | 0 | 54 | 8 | $1 |
| Redding, Tim | SD | 9 | 29.2 | 17 | 13 | 40 | 30 | 0 | 5 | 0 | 9.1 | 1.79 | $1 |
| Reed, Steve | BAL | 30 | 32.2 | 15 | 11 | 41 | 24 | 1 | 2 | 0 | 6.61 | 1.59 | $1 |
| Regilio, Nick | TEX | 18 | 17.2 | 14 | 7 | 22 | 9 | 1 | 2 | 0 | 4.58 | 1.64 | $1 |
| Remlinger, Mike | CHC | 35 | 33 | 30 | 12 | 31 | 18 | 0 | 3 | 0 | 4.91 | 1.3 | $1 |
| Remlinger, Mike | BOS | 8 | 6.2 | 5 | 5 | 15 | 11 | 0 | 0 | 0 | 14.85 | 3 | $1 |
| Resop, Chris | FLO | 15 | 17 | 15 | 9 | 22 | 16 | 2 | 0 | 0 | 8.47 | 1.82 | $1 |
| Reyes, Anthony | STL | 4 | 13.1 | 12 | 4 | 6 | 4 | 1 | 1 | 0 | 2.7 | 0.75 | $1 |
| Reyes, Dennys | SD | 36 | 43.2 | 35 | 32 | 57 | 25 | 3 | 2 | 0 | 5.15 | 2.04 | $1 |
| Riedling, John | FLO | 29 | 27.2 | 16 | 13 | 34 | 22 | 4 | 1 | 0 | 7.16 | 1.7 | $1 |
| Riley, Matt | TEX | 7 | 12.2 | 4 | 10 | 16 | 14 | 1 | 0 | 0 | 9.95 | 2.05 | $1 |
| Rincon, Ricardo | OAK | 67 | 37.1 | 27 | 20 | 34 | 18 | 1 | 1 | 0 | 4.34 | 1.45 | $1 |
| Ring, Royce | NYM | 15 | 10.2 | 8 | 10 | 10 | 6 | 0 | 2 | 0 | 5.06 | 1.88 | $1 |
| Rodriguez, Felix | NYY | 34 | 32.1 | 18 | 20 | 33 | 18 | 0 | 0 | 0 | 5.01 | 1.64 | $1 |
| Rodriguez, Ricardo | TEX | 12 | 57 | 24 | 17 | 67 | 35 | 2 | 3 | 0 | 5.53 | 1.47 | $1 |
| Rodriguez, Wandy | HOU | 25 | 128.2 | 80 | 53 | 135 | 79 | 10 | 10 | 0 | 5.53 | 1.46 | $1 |
| Rueter, Kirk | SF | 20 | 107.1 | 25 | 47 | 131 | 71 | 2 | 7 | 0 | 5.95 | 1.66 | $1 |
| Rupe, Josh | TEX | 4 | 9.2 | 6 | 4 | 7 | 3 | 1 | 0 | 0 | 2.79 | 1.14 | $1 |
| Sanders, David | CWS | 2 | 2 | 1 | 1 | 3 | 3 | 0 | 0 | 0 | 13.5 | 2 | $1 |
| Santana, Julio | MLW | 41 | 42 | 49 | 19 | 34 | 21 | 3 | 5 | 1 | 4.5 | 1.26 | $1 |
| Santiago, Jose | NYM | 4 | 5.2 | 3 | 2 | 10 | 2 | 0 | 0 | 0 | 3.18 | 2.12 | $1 |
| Santos, Victor | MLW | 29 | 141.2 | 89 | 60 | 153 | 72 | 4 | 13 | 0 | 4.57 | 1.5 | $1 |
| Sauerbeck, Scott | CLE | 58 | 35.2 | 35 | 16 | 35 | 16 | 1 | 0 | 0 | 4.04 | 1.43 | $1 |
| Saunders, Joe | ANA | 2 | 9.1 | 4 | 4 | 10 | 8 | 0 | 0 | 0 | 7.71 | 1.5 | $1 |
| Schmoll, Steve | LA | 48 | 46.2 | 29 | 22 | 47 | 26 | 2 | 2 | 3 | 5.01 | 1.48 | $1 |
| Schoeneweis, Scott | TOR | 80 | 57 | 43 | 25 | 54 | 21 | 3 | 4 | 1 | 3.32 | 1.39 | $1 |
| Seay, Bobby | COL | 17 | 11.2 | 11 | 8 | 18 | 11 | 0 | 0 | 0 | 8.49 | 2.23 | $1 |
| Sele, Aaron | SEA | 21 | 116 | 53 | 41 | 147 | 73 | 6 | 12 | 0 | 5.66 | 1.62 | $1 |
| Shackelford, Brian | CIN | 37 | 29.2 | 17 | 9 | 21 | 8 | 1 | 0 | 0 | 2.43 | 1.01 | $1 |
| Sherrill, George | SEA | 29 | 19 | 24 | 7 | 13 | 11 | 4 | 3 | 0 | 5.21 | 1.05 | $1 |
| Shouse, Brian | TEX | 64 | 53.1 | 35 | 18 | 55 | 31 | 3 | 2 | 0 | 5.23 | 1.37 | $1 |
| Simpson, Allan | CIN | 11 | 7.1 | 6 | 8 | 6 | 10 | 0 | 1 | 0 | 12.27 | 1.91 | $1 |
| Sisco, Andy | KC | 67 | 75.1 | 76 | 42 | 68 | 26 | 2 | 5 | 0 | 3.11 | 1.46 | $1 |
| Smith, Travis | FLO | 12 | 10.2 | 9 | 5 | 17 | 8 | 0 | 0 | 0 | 6.75 | 2.06 | $1 |
| Snell, Ian | PIT | 15 | 42 | 34 | 24 | 43 | 24 | 1 | 2 | 0 | 5.14 | 1.6 | $1 |
| Snyder, Kyle | KC | 13 | 36 | 19 | 10 | 55 | 27 | 1 | 3 | 0 | 6.75 | 1.81 | $1 |
| Soriano, Rafael | SEA | 7 | 7.1 | 9 | 1 | 6 | 2 | 0 | 0 | 0 | 2.45 | 0.95 | $1 |
| Speier, Ryan | COL | 22 | 24.2 | 10 | 13 | 26 | 10 | 2 | 1 | 0 | 3.65 | 1.58 | $1 |
| Standridge, Jason | CIN | 32 | 31 | 17 | 16 | 38 | 14 | 2 | 2 | 0 | 4.06 | 1.74 | $1 |
| Standridge, Jason | TEX | 2 | 2.1 | 2 | 1 | 7 | 3 | 0 | 0 | 0 | 11.57 | 3.43 | $1 |
| Stanton, Mike | WAS | 30 | 27.2 | 14 | 9 | 31 | 11 | 2 | 1 | 0 | 3.58 | 1.45 | $1 |
| Stanton, Mike | BOS | 29 | 15 | 13 | 6 | 18 | 11 | 1 | 2 | 0 | 6.6 | 1.6 | $1 |
| Stauffer, Tim | SD | 15 | 81 | 49 | 29 | 92 | 48 | 3 | 6 | 0 | 5.33 | 1.49 | $1 |
| Stemle, Steve | KC | 6 | 10.2 | 9 | 4 | 10 | 6 | 0 | 0 | 0 | 5.06 | 1.31 | $1 |
| Stone, Ricky | CIN | 23 | 30.2 | 15 | 7 | 48 | 23 | 0 | 0 | 0 | 6.75 | 1.79 | $1 |
| Strickland, Scott | HOU | 5 | 4 | 2 | 0 | 4 | 3 | 0 | 0 | 0 | 6.75 | 1 | $1 |
| Sturtze, Tanyon | NYY | 64 | 78 | 45 | 27 | 76 | 41 | 5 | 3 | 1 | 4.73 | 1.32 | $1 |
| Switzer, Jon | TB | 2 | 4 | 5 | 7 | 5 | 3 | 0 | 0 | 0 | 6.75 | 3 | $1 |
| Tadano, Kazuhito | CLE | 1 | 4 | 1 | 0 | 4 | 1 | 0 | 0 | 0 | 2.25 | 1 | $1 |
| Tallet, Brian | CLE | 2 | 4.2 | 2 | 3 | 6 | 4 | 0 | 0 | 0 | 7.71 | 1.93 | $1 |
| Taschner, Jack | SF | 24 | 22.2 | 19 | 13 | 15 | 4 | 2 | 0 | 0 | 1.59 | 1.24 | $1 |
| Tejera, Michael | TEX | 3 | 2 | 2 | 1 | 5 | 3 | 0 | 0 | 0 | 13.5 | 3 | $1 |
| Telemaco, Amaury | PHI | 7 | 10.2 | 8 | 4 | 5 | 5 | 0 | 1 | 0 | 4.22 | 0.84 | $1 |
| Thompson, Derek | LA | 4 | 18 | 13 | 10 | 16 | 7 | 0 | 0 | 0 | 3.5 | 1.44 | $1 |
| Thompson, Justin | TEX | 2 | 1.2 | 1 | 0 | 4 | 4 | 0 | 0 | 0 | 21.6 | 2.4 | $1 |
| Thornton, Matt | SEA | 55 | 57 | 57 | 42 | 54 | 33 | 0 | 4 | 0 | 5.21 | 1.68 | $1 |
| Tsao, Chin-Hui | COL | 10 | 11 | 4 | 5 | 16 | 8 | 1 | 0 | 3 | 6.55 | 1.91 | $1 |
| Tucker, T.J. | WAS | 13 | 12.2 | 5 | 2 | 20 | 9 | 1 | 0 | 0 | 6.39 | 1.74 | $1 |
| Valdez, Ismael | FLO | 14 | 50.2 | 27 | 22 | 64 | 30 | 2 | 2 | 0 | 5.33 | 1.7 | $1 |
| Valentine, Joe | CIN | 16 | 14.1 | 9 | 11 | 18 | 13 | 0 | 1 | 0 | 8.16 | 2.02 | $1 |
| Van Buren, Jermain | CHC | 6 | 6 | 3 | 9 | 2 | 2 | 0 | 2 | 0 | 3 | 1.83 | $1 |
| Vargas, Claudio | ARZ | 25 | 132.1 | 95 | 47 | 146 | 77 | 9 | 9 | 0 | 5.24 | 1.46 | $1 |
| Vargas, Jason | FLO | 17 | 73.2 | 59 | 31 | 71 | 33 | 5 | 5 | 0 | 4.03 | 1.38 | $1 |
| Vasquez, Jorge | ATL | 7 | 9 | 9 | 5 | 11 | 3 | 1 | 0 | 0 | 3 | 1.78 | $1 |
| Verlander, Justin | DET | 2 | 11.1 | 7 | 5 | 15 | 9 | 0 | 2 | 0 | 7.15 | 1.76 | $1 |
| Villarreal, Oscar | ARZ | 11 | 13.2 | 5 | 6 | 11 | 8 | 2 | 0 | 0 | 5.27 | 1.24 | $1 |
| Vogelsong, Ryan | PIT | 44 | 81.1 | 52 | 40 | 82 | 40 | 2 | 2 | 0 | 4.43 | 1.5 | $1 |
| Volquez, Edison | TEX | 6 | 12.2 | 11 | 10 | 25 | 20 | 0 | 4 | 0 | 14.21 | 2.76 | $1 |
| Waechter, Doug | TB | 29 | 157 | 87 | 38 | 191 | 98 | 5 | 12 | 0 | 5.62 | 1.46 | $1 |
| Wagner, Ryan | CIN | 42 | 45.2 | 39 | 17 | 56 | 31 | 3 | 2 | 0 | 6.11 | 1.6 | $1 |
| Wainwright, Adam | STL | 2 | 2 | 0 | 1 | 2 | 3 | 0 | 0 | 0 | 13.5 | 1.5 | $1 |
| Walker, Kevin | CWS | 9 | 7 | 5 | 5 | 10 | 7 | 0 | 1 | 0 | 9 | 2.14 | $1 |
| Webb, John | TB | 1 | 4 | 2 | 4 | 6 | 8 | 0 | 1 | 0 | 18 | 2.5 | $1 |
| Weber, Ben | CIN | 10 | 12.1 | 8 | 9 | 20 | 11 | 0 | 0 | 0 | 8.03 | 2.35 | $1 |
| Wellemeyer, Todd | CHC | 22 | 32.1 | 32 | 22 | 32 | 22 | 2 | 1 | 1 | 6.12 | 1.67 | $1 |
| Wells, Kip | PIT | 33 | 182 | 132 | 99 | 186 | 103 | 8 | 18 | 0 | 5.09 | 1.57 | $1 |
| White, Gabe | STL | 6 | 8.1 | 1 | 1 | 14 | 2 | 0 | 0 | 0 | 2.16 | 1.8 | $1 |
| White, Matt J | WAS | 1 | 4 | 3 | 3 | 4 | 4 | 0 | 1 | 0 | 9 | 1.75 | $1 |
| White, Rick | PIT | 71 | 75 | 40 | 29 | 90 | 31 | 4 | 7 | 2 | 3.72 | 1.59 | $1 |
| Whiteside, Matt | TOR | 2 | 3.2 | 5 | 5 | 6 | 8 | 0 | 0 | 0 | 19.64 | 3 | $1 |
| Williams, Randy | COL | 32 | 26.1 | 21 | 13 | 33 | 20 | 3 | 1 | 0 | 6.84 | 1.75 | $1 |
| Williamson, Scott | CHC | 17 | 14.1 | 23 | 6 | 15 | 9 | 0 | 0 | 0 | 5.65 | 1.47 | $1 |
| Wilson, C.J. | TEX | 24 | 48 | 30 | 18 | 63 | 37 | 1 | 7 | 1 | 6.94 | 1.69 | $1 |
| Wilson, Paul | CIN | 9 | 46.1 | 30 | 17 | 68 | 40 | 1 | 5 | 0 | 7.77 | 1.83 | $1 |
| Witasick, Jay | COL | 32 | 35.2 | 40 | 12 | 27 | 10 | 0 | 4 | 0 | 2.52 | 1.09 | $1 |
| Witasick, Jay | OAK | 28 | 27.2 | 33 | 17 | 26 | 10 | 1 | 1 | 1 | 3.25 | 1.55 | $1 |
| Wolf, Randy | PHI | 13 | 80 | 61 | 26 | 87 | 39 | 6 | 4 | 0 | 4.39 | 1.41 | $1 |
| Wood, Mike | KC | 47 | 115 | 60 | 52 | 129 | 57 | 5 | 8 | 2 | 4.46 | 1.57 | $1 |
| Woods, Jake | ANA | 28 | 27.2 | 20 | 8 | 30 | 14 | 1 | 1 | 0 | 4.55 | 1.37 | $1 |
| Woodyard, Mark | DET | 3 | 6 | 3 | 0 | 4 | 1 | 0 | 0 | 0 | 1.5 | 0.67 | $1 |
| Wright, Jamey | COL | 34 | 171.1 | 101 | 81 | 201 | 104 | 8 | 16 | 0 | 5.46 | 1.65 | $1 |
| Wunsch, Kelly | LA | 45 | 23.2 | 22 | 14 | 20 | 12 | 1 | 1 | 0 | 4.56 | 1.44 | $1 |
| Yabu, Keiichi | OAK | 40 | 58 | 44 | 26 | 64 | 29 | 4 | 0 | 1 | 4.5 | 1.55 | $1 |
| Yan, Esteban | ANA | 49 | 66.2 | 45 | 30 | 66 | 34 | 1 | 1 | 0 | 4.59 | 1.44 | $1 |
| Zambrano, Victor | NYM | 31 | 166.1 | 112 | 77 | 170 | 77 | 7 | 12 | 0 | 4.17 | 1.48 | $1 |